Human CellExp™ CD155, IgG2a Fc Tag, Mouse Recombinant

• Catalog number
  P1237-10
• Price
  Please ask
• Size
  10 ug

• Synonyms
  PVR, FLJ25946, PVS, CD155, TAGE4, HVED, NECL5
• Alternative_names
  PVR, FLJ25946, PVS, CD155, TAGE4, HVED, NECL5
• Description
  Establishes intercellular adherens junctions between epithelial cells
• Recombinant
  Yes
• Source
  HEK 293 cells
• Purity by SDS PAGE
  > 95%
• Assay
  SDS-PAGE
• Endotoxin Level
  < 1.0 EU per/ug
• Activity Specifications test method
  Measured by its binding ability in a functional ELISA.
• Binding Capacity
  Immobilized Mouse TIGIT, His Tag at 10 ug/mL (100 uL/well) can bind Mouse CD155, mouse IgG2a Fc tag with a linear range of 0.039-1.25 ug/mL mL.
• Molecular Weight
  61.8 kDa
• Storage Temp
  -20°C
• Shipping
  Gel Pack
• Shelf Life
  12 months
• Appearance
  Lyophilized
• Physical form description
  Lyophilized from 0.22 um filtered solution in 50 mM Tris, 100 mM Glycine, pH 7.5. Normally trehalose is added as protectant before lyophilization.
• Reconstitution Instructions
  Reconstitute in sterile deionized water to a concentration of 50 µg/ml.
• Background Information
  CD155 (cluster of differentiation 155) also known as the poliovirus receptor is a protein that is encoded by the PVR gene. CD155 is a Type I transmembrane glycoprotein in the immunoglobulin superfamily. Commonly known as Poliovirus Receptor (PVR) due to its involvement in the cellular poliovirus infection in primates, CD155's normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. The role of CD155 in the immune system is unclear, though it may be involved in intestinal humoral immune responses. Subsequent data has also suggested that CD155 may also be used to positively select MHC-independent T cells in the thymus.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  CellExp™   CD155   IgG2a   Tag  
• Gene symbol
  PVR
• Short name
  CellExp™ CD155, IgG2a Fc Tag, Mouse Recombinant
• Technique
  Recombinant, Mouse, FC, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
• Host
  mouse
• Isotype
  IgG2a
• Label
  Fc Tag
• Species
  Humans, Mouses
• Alternative name
  H. sapiens CellExp™ CD155, IgG2a fragment c detection labelled, Mouse Rec.
• Alternative technique
  rec, murine

Gene info

• Identity
  HGNC:9705
• Gene
  PVR
• Long gene name
  PVR cell adhesion molecule
• Synonyms gene
  • PVS
• Synonyms gene name
  • poliovirus receptor
• Synonyms
  • CD155
  • HVED
  • Necl-5
  • NECL5
  • Tage4
• Synonyms name
  • nectin-like 5
• GenBank acession
  • BC015542
• Locus
  19q13.31
• Discovery year
  2001-06-22
• Entrez gene record
  5817
• Pubmed identfication
  • 2170108
  • 28870470
• RefSeq identity
  • NM_006505
• Classification
  • Nectins and nectin-like molecules
  • CD molecules
  • C2-set domain containing
  • V-set domain containing
• VEGA ID
  OTTHUMG00000151527
• Locus Specific Databases
  • ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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