Protein L

• Catalog number
  6530-10
• Price
  Please ask
• Size
  10 mg

• Synonyms
  Protein L
• Alternative_names
  Protein L
• Description
  Genetically engineered protein ideal for purification of polyclonal or monoclonal IgG antibodies
• Recombinant
  Yes
• Source
  E. coli
• Purity by SDS PAGE
  ≥98%
• Assay
  SDS-PAGE
• Binding Capacity
  Under optimal conditions, 1 mg protein L will bind approximately 5 mg human IgG. Optimal binding of Protein L to antibodies occurs at pH 7.5 over a pH range of 2.5 to 3.0.
• Molecular Weight
  43.2 kDa with 5 IgG binding sites
• Storage Temp
  -20°C
• Shipping
  Gel Pack
• Shelf Life
  12 months
• Appearance
  Lyophilized
• Physical form description
  Lyophilized with no additives
• Reconstitution Instructions
  Reconstitution in H₂O to a concentration of 5 mg/ml gives a clear solution.
• Background Information
  Protein L has the unique ability to bind through kappa light chain interactions without interfering with the antibody’s antigen-binding site. This gives Protein L the ability to bind a wider range of Ig classes and subclasses than other antibody-binding proteins. Protein L can be used to detect, quantify and purify antibodies and antibody/antigen complexes. BioVision’s Recombinant Protein L contains only IgG binding domains. The albumin-binding domain as well as cell wall and cell membrane binding domains have been removed to ensure the maximum specific IgG binding capacity. The 6-His-tag on N-terminus can be used for affinity purification or protein L detection using anti-His-tag antibodies. Protein L binds to all classes of Ig (IgG, IgM, IgA, IgE, and IgD). Protein L will also bind Single Chain Variable Fragments (ScFv) and Fab Fragments. Protein L binds kappa I, III, and IV in human and kappa I on mouse.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet

• Gene target
  Protein  
• Gene symbol
  LCP1, PGLYRP2, ATRN
• Short name
  Protein L
• Alternative name
  Protein L

Gene info

• Identity
  HGNC:6528
• Gene
  LCP1
• Long gene name
  lymphocyte cytosolic protein 1
• Synonyms gene name
  • lymphocyte cytosolic protein 1 (L-plastin)
• Synonyms
  • PLS2
  • CP64
  • L-PLASTIN
  • LC64P
• Synonyms name
  • plastin 2
• GenBank acession
  • M22300
• Locus
  13q14.13
• Discovery year
  1986-01-01
• Entrez gene record
  3936
• Pubmed identfication
  • 2111166
• RefSeq identity
  • NM_002298
• Classification
  • EF-hand domain containing
• VEGA ID
  OTTHUMG00000016864

Gene info

• Identity
  HGNC:30013
• Gene
  PGLYRP2
• Long gene name
  peptidoglycan recognition protein 2
• Synonyms
  • PGRP-L
  • PGLYRPL
  • TAGL-like
  • tagL
  • tagL-alpha
  • tagl-beta
  • PGRPL
• Synonyms name
  • peptidoglycan recognition protein L precursor
  • peptidoglycan recognition protein-like
  • N-acetylmuramoyl-L-alanine amidase
• GenBank acession
  • AY358156
• Locus
  19p13.12
• Discovery year
  2004-03-17
• Entrez gene record
  114770
• Pubmed identfication
  • 11461926
  • 12669421
  • 14506276
• RefSeq identity
  • NM_052890
• Classification
  • Peptidoglycan recognition proteins
• VEGA ID
  OTTHUMG00000150690

Gene info

• Identity
  HGNC:885
• Gene
  ATRN
• Long gene name
  attractin
• Synonyms
  • DPPT-L
  • MGCA
• Synonyms name
  • mahogany protein
• GenBank acession
  • AF034957
• Locus
  20p13
• Discovery year
  1998-10-30
• Entrez gene record
  8455
• Pubmed identfication
  • 9736737
  • 8596018
• RefSeq identity
  • NM_139321
• Classification
  • C-type lectin domain containing
• VEGA ID
  OTTHUMG00000031746

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