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Anti-Giantin/GM130 (Polyclonal), ALEXA Fluor 594

Anti-Giantin/GM130 (Polyclonal), ALEXA Fluor 594 is available 1 time from Bioss polyclonal antibodies labs

GENTObs-13356R-A594 | Anti-Giantin/GM130 (Polyclonal), ALEXA Fluor 594 size: 100 microliters | 552.81 USD

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Modification No modification has been applied to this antibody
Clonality Polyclonal Antibody
Other name Anti-Giantin/GM130 Polyclonal
Host organism Rabbit (Oryctolagus cuniculus)
Background information GM130, a cis-Golgi matrix protein, interacts specifically with p115 and provides a membrane docking site. Both GM130 and p115 are involved in vesicle tethering to Golgi membranes. The protein p115 also binds p400, alternatively called giantin. Giantin, the majority of whose mass projects into the cytoplasm, is involved in the docking of COPI vesicles via p115 to the Golgi membrane. Giantin, which also is known as macrogolgin or Golgi complex-associated protein, is involved in cross-bridge formation in the Golgi complex. Giantin, which can form a homodimer, is a single-pass type I membrane protein that is an antigen in Sjoegren syndrome and in chronic rheumatoid arthritis.
Also known as Giantin/GM130 Polyclonal Antibody
Swiss Prot N/A
Specificity This antibody reacts specifically with Giantin/GM130
Modification site None
Applications with corresponding dilutions IF(IHC-P)(1:50-200)
Conjugated with ALEXA FLUOR® 594
Gene ID 2804
Clone Polyclonal Antibodies
Cross Reactive Species details No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
Synonyms 372 kDa Golgi complex associated protein; 372 kDa Golgi complex-associated protein; GCP; GCP372; Giantin; GOGB1_HUMAN; GOLGB1; Golgi autoantigen golgin subfamily a member 1; Golgi autoantigen golgin subfamily b macrogolgin with transmembrane signal 1; Golgi autoantigen, golgin subfamily b, macrogolgin 1; Golgi complex associated protein 372kDa; Golgi complex associated protein 372kDa; Golgi complex-associated protein 372kDa; Golgi complex-associated protein 372kDa; Golgin B1; Golgin B1, golgi integral membrane protein; Golgin subfamily B member 1; GOLIM1; Macrogolgin; Macrogolgin; MGC33154.
Applications IF(IHC-P)
Subcellular locations N/A
Concentration 1ug per 1ul
Purification method Purified by Protein A.
Advisory Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
Type Conjugated Primary Antibody
Cross reactive species Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
Excitation emission 590nm/617nm
Storage Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Target Protein/Peptide Giantin/GM130
Antigen Source KLH conjugated synthetic peptide derived from human Giantin/GM130
Properties For facs or microscopy Alexa 1 conjugate.
Conjugation Alexa Fluor,ALEXA FLUOR® 594
Conjugated Alexa conjugate 1
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Group Polyclonals and antibodies
About Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
Gene targetGiantin/GM130
Short name Anti-Giantin/GM130 (Polyclonal)
Technique Polyclonal, anti
Label ALEXA FLUOR 594
Alternative name antibody to-Giantin/GM130 (polyclonal), ALEXA Fluor 594
Alternative technique polyclonals
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