PathwayReady™ MAP Kinase Signaling Inhibitor Panel
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Catalog numberK862-7
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PricePlease ask
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Size7 inhibitors
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Alternative_nameMAP Kinase Signaling Inhibitor Panel, PathwayReady™
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DescriptionA convenient set consisting of seven inhibitors useful for the study of MAP Kinase signaling pathway. The seven inhibitors are: 1 mg of PD 184352 (Cat. No. 1585-1), 5 mg of PD 98059 (Cat. No. 1666-5), 1 mg of SB 203580 (Cat. No. 1712-1), 25 mg of Sorafenib (Cat. No. 1594-25), 5 mg of SP 600125 (Cat. No. 1669-5), 5 mg of U0126 (Cat. No. 1668-5), and 1 mg of ZM 336372 (Cat. No. 1789-1).
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CAS NumberSee under the individual product
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Structure AvailableSee under the individual product
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Salt FormNo
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Molecular FormulaSee under the individual product
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Molecular WeightSee under the individual product
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Cell PermeableYes
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Purity≥95% by HPLC
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SolubilitiesDMSO
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HandlingProtect from air and light
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Tag LineA MAP kinase pathway inhibitors set
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life24 months
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SMILESN/A
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InChiN/A
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InChi KeyN/A
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MSDS AvailableYes
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Additional descriptionTissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme. Cell nucleus signaling proteins and molecules are part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in cellular information processing are responsible for diseases such as cancer, autoimmunity, and diabetes. By understanding cell signaling, diseases may be treated effectively and, theoretically, artificial tissues may be created.
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Gene target
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Gene symbolMOAP1, MAP7, MASP2, MASP1
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Short namePathwayReady™ MAP Kinase Signaling Inhibitor Panel
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Alternative namePathwayReady™ mitogen-stimulated protein kinase phosphorylation catalyst Signaling suppressor Panel
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Tissuepanel
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Gene info
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Identity
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Gene
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Long gene namemodulator of apoptosis 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2002-11-13
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Entrez gene record
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Pubmed identfication
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Classification
- Paraneoplastic Ma antigens
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicrotubule associated protein 7
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-01-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameMBL associated serine protease 2
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Synonyms gene
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Synonyms gene name
- mannan-binding lectin serine protease 2
- mannan-binding lectin serine peptidase 1 pseudogene 1
- mannan-binding lectin serine protease 1 pseudogene 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-12-17
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Sushi domain containing
- Complement system activation components
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameMBL associated serine protease 1
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Synonyms gene
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Synonyms gene name
- mannan-binding lectin serine protease 1 (C4/C2 activating component of Ra-reactive factor)
- mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
- mannan binding lectin serine peptidase 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1995-07-06
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Serine proteases
- Complement system activation components
- Sushi domain containing
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Recording of pertinent information concerning patient's illness or illnesses.
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Tree numbers
- E05.318.308.940.968
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Qualifiersclassification, economics, legislation & jurisprudence, standards, statistics & numerical data