Recombinant Human ILT6 / LILRA3 Protein (Fc tag) 100µg

• Catalog number
  PKSH030602-100µg
• Price
  Please ask
• Size
  100µg

• Synonym
  CD85e;HM31;HM43;ILT-6;ILT6;LIR-4;LIR4
• Activity
  NA
• Sequence
  Met1-Glu439
• Fusion tag
  C-Fc
• Accession
  AAH28208.1
• Expressed Host
  HEK293 Cells
• Shipping
  In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
• Purity
  ＞80 % as determined by SDS-PAGE
• Endotoxin
  ＜1.0 EU per µg as determined by the LAL method
• Stability and Storage
  Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Mol Mass
  72 kDa
• AP Mol Mass
  102 kDa
• Formulation
  Lyophilized from sterile PBS, pH 7.4
• Reconstitution
  Please refer to it for detailed information.
• Background
  ILT6, also known as LILRA3, belongs to the ILT family. In human, the ILT gene family includes up to 11 members. The extracellular portion of all members includes at least two and usually four immuno-globulin domains. ILT-2 through 5 are all inhibitory members having variable numbers of cytoplasmic ITIM domains. ILT6 lacks a transmembrane domain. The function of ILT6 is currently unknown. however it is highly homologous to other LILR genes, and can bind human leukocyte antigen (HLA) class I. Therefore, if secreted, the ILT6 might impair interactions of membrane-bound LILRs (such as LILRB1, an inhibitory receptor expressed on effector and memory CD8 T cells) with their HLA ligands, thus modulating immune reactions and influencing susceptibility to disease.
• Product URL
• PDF URL
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  ILT6   LILRA3   Protein   tag   100µg  
• Gene symbol
  LILRA3
• Short name
  Recombinant ILT6 / LILRA3 Protein (Fc tag) 100µg
• Technique
  Recombinant, FC, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
• Label
  Fc Tag
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens ILT6 / LILRA3 Protein (fragment c detection labelled) 100µg
• Alternative technique
  rec

Gene info

• Identity
  HGNC:6604
• Gene
  LILRA3
• Long gene name
  leukocyte immunoglobulin like receptor A3
• Synonyms gene name
  • leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3
• Synonyms
  • LIR-4
  • HM43
  • ILT6
  • HM31
  • LIR4
  • CD85e
• Synonyms name
  • leucocyte Ig-like receptor A3
• GenBank acession
  • U91926
• Locus
  19q13.4 alternate reference locus
• Discovery year
  2000-01-11
• Entrez gene record
  11026
• Pubmed identfication
  • 9278324
  • 9548455
• Classification
  • Activating leukocyte immunoglobulin like receptors
  • CD molecules

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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