Recombinant Rat Glucagon receptor (Gcgr)[Glucagon receptor (Gcgr)]

Products_type

Recombinant Protein
Description

Glucagon gene and the glucagon like peptide or GLP1 gene are peptide hormones, produced by alpha cells of the pancreas to raise the concentration of glucose in the blood as opposite of insulin, which lowers the glucose. Anti human glucagon and glp1 antibodies are used to study diabetes. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
About

Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
Latin name

Rattus norvegicus
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

Glucagon receptor Gcgr [Glucagon receptor Gcgr
Gene symbol

GCGR
Short name

Recombinant Glucagon receptor (Gcgr)[Glucagon receptor (Gcgr)]
Technique

Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Host

E Coli or Yeast or Baculovirus or Mammalian Cell
Species

Rat, Rats
Alternative name

Rec. Rat Glucagon receptor (gluca this GO n receptor)[Glucagon receptor (gluca this GO n receptor)]
Alternative technique

rec
Alternative to gene target

gluca this GO n receptor, GGR and GL-R, GCGR and IDBG-227533 and ENSG00000215644 and 2642, peptide hormone binding, Plasma membranes, Gcgr and IDBG-214830 and ENSMUSG00000025127 and 14527, BT.27844 and IDBG-642400 and ENSBTAG00000003786 and 515433

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data