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NAME hydrochloride

NAME hydrochloride is available 6 times from Biovision labs

2356-1000 | L-NAME hydrochloride size: 1 g | 430.13 USD

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2356-100 | L-NAME hydrochloride size: 2X100 mg | 321.16 USD

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2356-500 | L-NAME hydrochloride size: 500 mg | 395.72 USD

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2356-100 | L-NAME hydrochloride for cell activation size: 100 mg | 138.79 USD

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2356-500 | L-NAME hydrochloride for cell activation size: 500 mg | 300.51 USD

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2356-1000 | L-NAME hydrochloride for cell activation size: 1 g | 338.37 USD

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Description A pro-drug of L- NG-Nitro-L-arginine (L-NOARG). Hydrolysis of the methyl ester of L-NAME by cellular esterases converts it into a fully functional L-NOARG that exhibits some selectivity for inhibition of neuronal and endothelial NOS isoforms (Ki values of 15 nM, 39 nM, and 4.4 µM for nNOS (bovine), eNOS (human), and iNOS (mouse), respectively). L-NAME inhibits cGMP formation in endothelial cells with an IC₅₀ of 3.1 µM (in the presence of 30 µM arginine) and reverses the vasodilation effects of acetylcholine in rat aorta rings with an EC₅₀ of 0.54 µM.
Peptide sequence H-Arg(NO2)-OMeHCl
CAS number 51298-62-5
Molecular weight 269.69
Category Biochemicals
Other name NG-Nitro-L-arginine methyl ester hydrochloride
Molecular formula C₇H₁₅N₅O₄.HCl
Physical appearance White solid
Supplied with N/A
Is this a salt? Yes
Is it cell-permeable? Yes
Purification ≥98%
Reconstitute instructions DMSO (~ 5 mg/ml) or H2O (~50 mg/ml)
Storage condition -20°C
Shipping condition gel pack
Maximum time for storage 36 months
Storage instructions Protect from air and moisture
Alternate Name/Synonyms NG-Nitro-L-arginine methyl ester hydrochloride
Appearance White solid
Formulation N/A
CAS Number 51298-62-5
Molecular Formula C₇H₁₅N₅O₄.HCl
Molecular Weight 269.69
Purity ≥98%
Solubility/Reconstitution Instructions DMSO (~ 5 mg/ml) or H2O (~50 mg/ml)
Handling Protect from air and moisture
Tagline A pro-drug of the NOS inhibitor L- NG-Nitro-L-arginine
Storage Temp. -20°C
Shipping Conditions gel pack
Shelf Life 36 months
MDL Number MFCD00039052
PubChem CID 135193
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