Recombinant Human Cadherin-11/OB-Cadherin/CDH11 (C-Fc-6His)

• Catalog number
  CB83-10
• Price
  Please ask
• Size
  10 ug

• Description
  Recombinant Human Cadherin-11 is produced by our Mammalian expression system and the target gene encoding Phe23-Thr617 is expressed with a Fc, 6His tag at the C-terminus.
• Species reactivity
  Human
• Origin
  Human cells
• Peptide sequence
  FAPERRGHLRPSFHGHHEKGKEGQVLQRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVMITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFISNGPFKDTVTVKIAVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQEAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGALLSCNAEAYILNAGLSTVDDIEGRMDEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH
• Estimated molecular weight
  93,5 kDa
• Protein purity
  Greater than 95% as determined by reducing SDS-PAGE.
• Endotoxin level
  Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
• Shipping condition
  Ambient/Room Temperature
• Package form
  Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4 .
• Storage conditions
  Lyophilized protein should be stored at below -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at below -20°C for 3 months.
• Reconstitution conditions
  Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 µg/ml.Dissolve the lyophilized protein in ddH2O.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
• UniProt number
  Q96CZ9
• Other related products
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Cadherin-11/OB-Cadherin/CDH11   C-Fc-6His  
• Gene symbol
  CDH11, LEP, LEPROT, SIGLEC5, SIGLEC6
• Short name
  Recombinant Cadherin-11/OB-Cadherin/CDH11 (C-Fc-6His)
• Technique
  Recombinant, FC, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Human Cadherin-11/OB-Cadherin/CDH11(C-Fc-6His)
• Alternative technique
  rec
• Alternative to gene target
  cadherin 11, type 2, OB-cadherin (osteoblast), CAD11 and CDHOB and OB and OSF-4, CDH11 and IDBG-34793 and ENSG00000140937 and 1009, calcium ion binding, Plasma membranes, Cdh11 and IDBG-184962 and ENSMUSG00000031673 and 102642711,12552, CDH11 and IDBG-633028 and ENSBTAG00000032092 and 785475

Gene info

• Identity
  HGNC:1750
• Gene
  CDH11
• Long gene name
  cadherin 11
• Synonyms gene name
  • cadherin 11, type 2, OB-cadherin (osteoblast)
• Synonyms
  • OB
  • CAD11
• Synonyms name
  • OB-Cadherin
• GenBank acession
  • D21255
• Locus
  16q21
• Discovery year
  1995-03-30
• Entrez gene record
  1009
• Pubmed identfication
  • 9615235
• RefSeq identity
  • NM_033664
• Classification
  • Type II classical cadherins
• VEGA ID
  OTTHUMG00000137494

Gene info

• Identity
  HGNC:6553
• Gene
  LEP
• Long gene name
  leptin
• Synonyms gene
  • OBS
  • OB
• Synonyms gene name
  • leptin (murine obesity homolog)
  • leptin (obesity homolog, mouse)
• Locus
  7q32.1
• Discovery year
  1993-01-26
• Entrez gene record
  3952
• Pubmed identfication
  • 1686014
  • 16932309
• Classification
  • Neuropeptides
• VEGA ID
  OTTHUMG00000157564

Gene info

• Identity
  HGNC:29477
• Gene
  LEPROT
• Long gene name
  leptin receptor overlapping transcript
• Synonyms
  • OBRGRP
  • OB-RGRP
  • VPS55
  • FLJ90360
• Synonyms name
  • leptin receptor gene related protein
  • endospanin-1
  • endospanin
• GenBank acession
  • Y12670
• Locus
  1p31.3
• Discovery year
  2004-11-16
• Entrez gene record
  54741
• Pubmed identfication
  • 9207021
  • 21454707
• RefSeq identity
  • NM_017526
• VEGA ID
  OTTHUMG00000009065

Gene info

• Identity
  HGNC:10874
• Gene
  SIGLEC5
• Long gene name
  sialic acid binding Ig like lectin 5
• Synonyms gene
  • CD33L2
• Synonyms gene name
  • sialic acid binding Ig-like lectin 5
• Synonyms
  • OB-BP2
  • SIGLEC-5
  • CD170
• GenBank acession
  • U71383
• Locus
  19q13.41
• Discovery year
  1998-12-16
• Entrez gene record
  8778
• Pubmed identfication
  • 10343116
• RefSeq identity
  • NM_003830
• Classification
  • CD molecules
  • Sialic acid binding Ig like lectins
  • V-set domain containing
• VEGA ID
  OTTHUMG00000165510

Gene info

• Identity
  HGNC:10875
• Gene
  SIGLEC6
• Long gene name
  sialic acid binding Ig like lectin 6
• Synonyms gene
  • CD33L
  • CD33L1
• Synonyms gene name
  • sialic acid binding Ig-like lectin 6
• Synonyms
  • OB-BP1
  • SIGLEC-6
  • CD327
• GenBank acession
  • D86358
• Locus
  19q13.41
• Discovery year
  1996-12-17
• Entrez gene record
  946
• Pubmed identfication
  • 9465907
• RefSeq identity
  • NM_001245
• Classification
  • I-set domain containing
  • Sialic acid binding Ig like lectins
  • V-set domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000133571

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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