anti-Integrin beta 2 Antibody [MEM-48]

• Catalog number
  48-988
• Price
  Please ask
• Size
  0.05 mg

• Gene info
  CD18 is a 90-95 kDa type I transmembrane protein expressed on all leukocytes. The ITGB2 protein product is the integrin beta chain beta 2. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.
• Gene names
  ITGB2, CD18 antigen, CD18, Integrin beta chain, beta 2, LCAMB, MAC-1, MFI7, MF17, Integrin beta-2, LAD, LFA-1
• Antibodie s label
  unlabelled serum
• Purity
  Protein A Column
• Ab raised in
  Mouse
• Type
  Monoclonal
• Monoclonal
  [MEM-48]
• Immunoglobulin
  IgG1
• Spicific to
  Recongizes an epitope involving residues 534-546 in cysteine-rich repeat 3 of the CD18 antigen (integrin beta2 subunit; beta2 integrin).
• Antigen
  Integrin beta 2 monoclonal antibody was made against Integrin beta 2 (Human).
• Immuno application
  Western Blot, immuno-histo-chemistry, immuno precipitation, FLOW
• Antibody advice
  Integrin beta 2 antibody can be used in ELISA starting at 1:100000, Western Blot starting at 1:1000 - 1:10000, and immunohistochemistry starting at 5 ug/mL.
• Suspention pH azide
  PBS, 15 mM sodium azide, approx., pH 7.4.
• Keep at
  Integrin beta 2 antibody can be stored short term 4 grades C. For long term storage aliquot and store at -20 grades C. As with all antibodies avoid freeze/thaw cycles.
• Works with
  Human
• Omim nr
  124056465
• Ncbi nr
  P05107
• Vial with antibody
  in solution
• NCBI GENE nr
  3689
• GENE symbol
  ITGB2
• Antigene name
  integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
• Source
  Homo sapiens
• Protein nr
  P05107
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Integrin   beta   [MEM-48]  
• Gene symbol
  SNORD115-48, IGLV5-48, IGHV3-48, RNU6-48P, UTP18, HAUS8, SNORD115-45
• Short name
  anti-Integrin beta 2 Antibody [MEM-48]
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toIntegrin b 2 (antibody to-) [MEM-48]
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:33343
• Gene
  SNORD115-48
• Long gene name
  small nucleolar RNA, C/D box 115-48
• Synonyms
  • HBII-52-48
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-16
• Entrez gene record
  100033822
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003362.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:5925
• Gene
  IGLV5-48
• Long gene name
  immunoglobulin lambda variable 5-48 (non-functional)
• Synonyms gene name
  • immunoglobulin lambda variable 5-48
• GenBank acession
  • Z73649
• Locus
  22q11.22
• Discovery year
  2000-05-08
• Entrez gene record
  28780
• RefSeq identity
  • NG_000002
• Classification
  • Immunoglobulin lambda locus at 22q11.2
• VEGA ID
  OTTHUMG00000151041

Gene info

• Identity
  HGNC:5606
• Gene
  IGHV3-48
• Long gene name
  immunoglobulin heavy variable 3-48
• GenBank acession
  • M99675
• Locus
  14q32.33
• Discovery year
  2000-04-04
• Entrez gene record
  28424
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000151959

Gene info

• Identity
  HGNC:34292
• Gene
  RNU6-48P
• Long gene name
  RNA, U6 small nuclear 48, pseudogene
• Synonyms gene
  • RNU6-48
• Synonyms gene name
  • RNA, U6 small nuclear 48
• Locus
  1p36.11
• Discovery year
  2008-06-10
• Entrez gene record
  100887744
• RefSeq identity
  • NR_049779

Gene info

• Identity
  HGNC:24274
• Gene
  UTP18
• Long gene name
  UTP18 small subunit processome component
• Synonyms gene
  • WDR50
• Synonyms gene name
  • WD repeat domain 50
  • UTP18 small subunit (SSU) processome component homolog (yeast)
• Synonyms
  • CGI-48
• GenBank acession
  • AF151806
• Locus
  17q21.33
• Discovery year
  2005-02-01
• Entrez gene record
  51096
• Pubmed identfication
  • 10810093
  • 8619474
  • 15590835
• RefSeq identity
  • NM_016001
• Classification
  • UTPb subcomplex
  • WD repeat domain containing
• VEGA ID
  OTTHUMG00000162370

Gene info

• Identity
  HGNC:30532
• Gene
  HAUS8
• Long gene name
  HAUS augmin like complex subunit 8
• Synonyms gene
  • HICE1
• Synonyms gene name
  • HEC1/NDC80 interacting, centrosome associated 1
• Synonyms
  • MGC20533
  • NY-SAR-48
• GenBank acession
  • BC004398
• Locus
  19p13.11
• Discovery year
  2008-12-16
• Entrez gene record
  93323
• Pubmed identfication
  • 19427217
• RefSeq identity
  • NM_001011699
• Classification
  • HAUS augmin like complex
• VEGA ID
  OTTHUMG00000182672

Gene info

• Identity
  HGNC:33064
• Gene
  SNORD115-45
• Long gene name
  small nucleolar RNA, C/D box 115-45
• Synonyms
  • HBII-52-45
  • SNORD115-48
• Locus
  15q11.2
• Discovery year
  2011-08-22
• Entrez gene record
  100036566
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003498
• Classification
  • Small nucleolar RNAs, C/D box

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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