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anti-Bcl-xL Antibody

anti-Bcl-xL Antibody is available 1 time from Biovision labs

3312-100 | anti-Bcl-xL Antibody size: Bcl-xL Antibody | 437.44 USD

Catalog number 3312-100
Supplier Biovision
Price 437.44 USD
Size Bcl-xL Antibody
1. Gene info
Identity 992
Gene BCL2L1
Long gene name BCL2 like 1
Synonyms
  • BCLX
  • BCL2L
  • Bcl-X
  • bcl-xL
  • bcl-xS
  • PPP1R52
Synonyms name
  • protein phosphatase 1, regulatory subunit 52
GenBank acession
  • Z23115
Locus 20q11.21
Discovery year 1997-10-30
Entrez gene record 598
Pubmed identfication
  • 8358789
RefSeq identity
  • NM_138578
Classification
  • BCL2 family
  • Protein phosphatase 1 regulatory subunits
Havana BLAST/BLAT OTTHUMG00000032192
Product images
    #0#.jpegBcl-xL Antibody
Target of this antibody: Bcl-xl
Alternative names of antibody target: Bcl-xL, Bcl-xS, BCL2L1, BCL2-like 1 protein
Background information: Bcl-xL is a 30 kDa anti-apoptotic protein belonging to the Bcl-2 family. Bcl-xL prevents apoptosis throμgh two different mechanisms: by heterodimerization with an apoptotic protein to inhibit its apoptotic effect, and by its direct pore-forming effect on the outer-membrane of mitochondria to help maintain a normal membrane state under stress conditions. Bcl-xL can be cleaved by caspases upon apoptotic activation, which converts Bcl-xL from an antiapoptotic protein to a proapoptotic cleavage product. The cleavage product of Bcl-xL forms cytochrome c-releasing pores in the mitochondrial membrane to facilitate the apoptosis signaling pathway.
Antibody host: Rabbit
Clonality of antibody: Polyclonal
Isotype: Rabbit IgG
This antibody reacts with: Human, mouse, rat
Immunogene sequence: Synthetic peptide surrounding amino acid 56 of human Bcl-xL
Concentration of antibody: 0.5 mg/ml
Form of antibody: Liquid
Formulation of this antibody: 100 µg (0.5 mg/ml) affinity purified, rabbit anti-Bcl-xL polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Purification method: Affinity purified
This antibody has been succesfully tested for use in following methods: Western blot, Immunoprecipitation
Recommended usage: Western blotting (0.5-4 µg/ml) and immunoprecipitation (20 µ/ml). However, the optimal conditions should be determined individually. The antibody detects the 30 kDa Bcl-xL protein. It does not react with other Bcl-2 family members.
Storage information: Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions: gel pack
How to handle this antibody: The antibody solution should be gently mixed before use.
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation anticorps
Gene targetBcl-xL
Short name anti-Bcl-xL Antibody
Technique Antibody, anti
Alternative name antibody to-Bcl-xL (Antibody to)
Alternative technique antibodies
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anti-Bcl-xL Antibody | Technique alternative | 01012192146
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