Recombinant Mouse Alpha-1A adrenergic receptor (Adra1a)

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Description

The Recombinant Mouse Alpha-1A adrenergic receptor (Adra1a) is a α- or alpha protein sometimes glycoprotein present in blood. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
Test

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin name

Mus musculus
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

Alpha-1A adrenergic receptor Adra1a
Gene symbol

IGHD1OR15-1A, UBP1, MTNR1A, IGKV2OR2-1, SCLT1, APH1A, HIF1A-AS1, HIF1A-AS2, MARK3, H2BC8
Short name

Recombinant Mouse Alpha-1A adrenergic receptor (Adra1a)
Technique

Recombinant, Mouse, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Host

mouse
Species

Mouse, Mouses
Alternative name

Rec. Mouse a-1A adrenergic receptor (adrenoceptor a 1A)
Alternative technique

rec, murine
Alternative to gene target

adrenoceptor alpha 1A, ADRA1C and ADRA1L1 and ALPHA1AAR, ADRA1A and IDBG-13362 and ENSG00000120907 and 148, protein heterodimerization activity, nuclei, Adra1a and IDBG-175481 and ENSMUSG00000045875 and 11549, ADRA1A and IDBG-635639 and ENSBTAG00000031632 and 282134

Identity

HGNC:5805
Gene

IGKV2OR2-1
Long gene name

immunoglobulin kappa variable 2/OR2-1 (pseudogene)
Synonyms gene
- IGKV2OR2-1A
Synonyms gene name
- immunoglobulin kappa variable 2/OR2-1
- immunoglobulin kappa variable 2/OR2-1 pseudogene
Synonyms
- IGKV2/OR2-1
- IGKV2/OR2-1A
GenBank acession
- X05101
Locus

2q11.2
Discovery year

2000-04-18
Entrez gene record

28861
Pubmed identfication
- 8011175
Classification
- Immunoglobulin kappa (IGK) orphons
VEGA ID

OTTHUMG00000155332

Identity

HGNC:29509
Gene

APH1A
Long gene name

aph-1 homolog A, gamma-secretase subunit
Synonyms gene name
- anterior pharynx defective 1 homolog A (C. elegans)
- APH1A gamma secretase subunit
Synonyms
- APH-1A
- CGI-78
GenBank acession
- AF151835
Locus

1q21.2
Discovery year

2005-02-08
Entrez gene record

51107
Pubmed identfication
- 10810093
- 12110170
RefSeq identity
- NM_016022
VEGA ID

OTTHUMG00000012545

Identity

HGNC:4746
Gene

H2BC8
Long gene name

H2B clustered histone 8
Synonyms gene
- H2BFA
- HIST1H2BG
Synonyms gene name
- H2B histone family, member A
- histone 1, H2bg
- histone cluster 1, H2bg
- histone cluster 1 H2B family member g
Synonyms
- H2B/a
- H2B.1A
GenBank acession
- M60750
Locus

6p22.2
Discovery year

1998-08-27
Entrez gene record

8339
Pubmed identfication
- 1916825
- 12408966
RefSeq identity
- NM_003518
Classification
- H2B histones
VEGA ID

OTTHUMG00000014446

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data