A potent histone H3-lysine 27 (H3K27) methyltransferase EZH2 inhibitor (IC₅₀ = 4 nM). Diplays 1000-fold selectivity for other HMTs except EZH1 (60-fold selectivity). GSK343 inhibits H3K27 methylation in HCC1806 cells with an IC₅₀ of
Is it cell-permeable?
≥99% by HPLC
Is this a salt?
Protect from light and moisture
Maximum time for storage
For cells, cell lines and tissues in culture till half confluency.