Rabbit Anti Rat Dio3 Antibody-Biotin
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Catalog numberCSB-PA344617LD01RA_100ug
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PricePlease ask
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Size100ug
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Long nameRabbit Antibody against Rat Dio3, Biotin
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Synonym nameDio3 Rat Antibody
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Species reactivityRat
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Tested applications recommended dilutionsELISA
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ConjugationBiotin
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Antibody isotypeIgG
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UniProt IDP49897
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FormatLiquid, diluted in buffer
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Buffer compositionPreservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
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Purity>95%
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Purification methodProtein G purified
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Antibody categoryPolyclonal Antibodies
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Immunogen typeRecombinant rat Type III iodothyronine deiodinase protein (37-278AA)
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Immunogen speciesrat
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Alias5DIII,DIOIII,Type 3 DI,Type-III 5'-deiodinase,Dio3,Itdi3, Txdi3
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BackgroundResponsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into RT3 (3,3',5'-triiodothyronine) and of T3 (3,5,3'-triiodothyronine) into T2 (3,3'-diiodothyronine). RT3 and T2 are inactive metabolites. May play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones. Can regulate circulating fetal thyroid hormone concentrations throughout gestation. Essential role for regulation of thyroid hormone inactivation during embryological development.
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ClonalityPolyclonal antibody
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Shipping and storageDio3 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
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PropertiesIf you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
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Additional conjugationBiotinylated
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AboutRabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long. Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
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Latin nameOryctolagus cuniculus, Rattus norvegicus
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French translationanticorps
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Gene target
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Gene symbolDIO3, DIO3OS
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Short nameAnti-Dio3
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TechniqueAntibody, Rabbit, anti, antibody to, antibodies against human proteins, antibodies for
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HostRabbit, Rabbits
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LabelBiotin
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SpeciesRat, Rats
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Alternative nameDio3 Antibody,Biotin conjugated
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Alternative techniqueantibodies, rabbit-anti
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Gene info
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Identity
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Gene
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Long gene nameiodothyronine deiodinase 3
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Synonyms gene
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Synonyms gene name
- deiodinase, iodothyronine type III
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Synonyms name
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GenBank acession
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Locus
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Discovery year1996-04-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Selenoproteins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameDIO3 opposite strand upstream RNA
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Synonyms gene
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Synonyms gene name
- chromosome 14 open reading frame 134
- deiodinase, iodothyronine, type III opposite strand
- DIO3 opposite strand/antisense RNA
- DIO3 opposite strand/antisense RNA (head to head)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2003-01-28
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Long non-coding RNAs with non-systematic symbols
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data