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Lactacystin Proteasome inhibitor

Lactacystin Proteasome inhibitor is available 2 times from Stressma labs

SIH-327-1MG | Lactacystin, Proteasome inhibitor size: 1 mg | 849.96 USD

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SIH-327-200UG | Lactacystin, Proteasome inhibitor size: 200 µg | 329.80 USD

Catalog number SIH-327-200UG
Supplier stressma
Price 329.80 USD
Size 200 µg
Net weight (g) 0.0002
Stock availabilitIn Stock In Stock
CAS number 133343-34-7
Description Proteasome inhibitor
Molecular weight 376,4 g/mol
Primary research fields Cancer, Apoptosis, Cancer Growth Inhibitors, Proteasome Inhibitors
Other name (2R,3S,4R)-3-Hydroxy-2-[(1S)-1-hydroxy-2-methylpropyl]-4-methyl-5-oxo-2-pyrrolidinecarboxy-N-acetyl-L-cysteine thioester
Product category Small Molecules
Product type Inhibitor
Chemical formula C15H24N2O7S
Origin Synthetic
Purity pourcentage >98%
Soluble in Soluble in DMSO, Water or Ethanol
Physical appearance White Solid
Storage recommendations -20ºC
Shipping recommendations Shipped Ambient
Safety information Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S24/25- Avoid contact with skin and eyes
PubChem number 6610292
Scientific context Specific inhibitor of three proteolytic activities of the proteasome. Chymotrypsin-like activity is inhibited most potently followed by trypsin-like activity. Peptidyl-glutamyl peptide hydrolytic activity is relatively weak.
Bibliography 1. Omura S., et al. (1991) J. Antibiot. 44: 113. 2. Fenteany G., et al. (1995) Science 268: 726
Release date 6-Jun-2012
PubMed number Refer to PubMed
Tested applications To be tested
Tested reactivity To be tested
Representative figure legend Chemical structure of Lactacystin (SIH-327), a Proteasome inhibitor. CAS #: 133343-34-7. Molecular Formula: C15H24N2O7S. Molecular Weight: 376.4 g/mol. Chemical structure of Lactacystin, a Proteasome inhibitor (SIH-327). CAS # 133343-34-7. Molecular Formula: C15H24N2O7S.
Warning information Non-hazardous
Country of production Canada
Total weight (kg) 0.25
Additional description Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
Gene targetLactacystin Proteasome inhibitor
Short name Lactacystin, Proteasome inhibitor
Alternative name Lactacystin, protein degradation aggregate suppressor
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