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Lactacystin Proteasome inhibitor

Lactacystin Proteasome inhibitor is available 2 times from Stressma labs

SIH-327-1MG | Lactacystin, Proteasome inhibitor size: 1 mg | 795.35 USD

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Origin Synthetic
Soluble in Soluble in DMSO, Water or Ethanol
Other name (2R,3S,4R)-3-Hydroxy-2-[(1S)-1-hydroxy-2-methylpropyl]-4-methyl-5-oxo-2-pyrrolidinecarboxy-N-acetyl-L-cysteine thioester
PubMed number Refer to PubMed
Description Proteasome inhibitor
Warning information Non-hazardous
Representative figure legend Chemical structure of Lactacystin (SIH-327), a Proteasome inhibitor. CAS #: 133343-34-7. Molecular Formula: C15H24N2O7S. Molecular Weight: 376.4 g/mol. Chemical structure of Lactacystin, a Proteasome inhibitor (SIH-327). CAS # 133343-34-7. Molecular Formula: C15H24N2O7S.
Stock availabilitIn Stock In Stock
Molecular weight 376,4 g/mol
Purity pourcentage>98%
Chemical formula C15H24N2O7S
Tested applications To be tested
Primary research fields Cancer, Apoptosis, Cancer Growth Inhibitors, Proteasome Inhibitors
Total weight (kg) 0.25
Release date 6-Jun-2012
Scientific context Specific inhibitor of three proteolytic activities of the proteasome. Chymotrypsin-like activity is inhibited most potently followed by trypsin-like activity. Peptidyl-glutamyl peptide hydrolytic activity is relatively weak.
Product type Inhibitor
CAS number 133343-34-7
Safety information Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S24/25- Avoid contact with skin and eyes
Country of production Canada
Product category Small Molecules
Physical appearance White Solid
Tested reactivity To be tested
PubChem number 6610292
Bibliography 1. Omura S., et al. (1991) J. Antibiot. 44: 113. 2. Fenteany G., et al. (1995) Science 268: 726
Storage recommendations -20ºC
Shipping recommendations Shipped Ambient
Additional description Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
Short name Lactacystin, Proteasome inhibitor
Alternative name Lactacystin, protein degradation aggregate suppressor
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