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NU 7441 for cell activation

NU 7441 for cell activation is available 2 times from Biovision labs

B1117-5 | NU-7441 for cell activation size: 5 mg | 200.73 USD

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B1117-25 | NU-7441 for cell activation size: 25 mg | 625.12 USD

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Other name 8-(4-Dibenzothienyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-one; KU-57788
Supplied with N/A
Description NU-7441 is a potent and selective DNA-PK inhibitor (IC₅₀ = 14 nM). Displays selectivity for DNA-PK over a range of kinases including mTOR, PI 3-K, ATM and ATR. Also enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency, and attenuates nonhomologous end-joining (NHEJ).
Category Biochemicals
Molecular formula C₂₅H₁₉NO₃S
Is it cell-permeable? Yes
Molecular weight 413.49
Storage condition -20°C
Shipping condition gel pack
Purification ≥98% by HPLC
Peptide sequence N/A
Is this a salt? No
CAS number 503468-95-9
Storage instructions Protect from air and light
Maximum time for storage 36 months
Physical appearance Off-white solid
Reconstitute instructions DMSO (~ 2 mg/ml with gentle warming)
Additional description For cells, cell lines and tissues in culture till half confluency.
Gene targetNU-7441 for activation
Short name NU-7441 for activation
Technique activation
Alternative name NU-7441 to measure cellular activation
Tissue cell
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