Selectively impairs the G9a histone lysine methyltransferase (HMTase) and the generation of H3K9me2 in vitro. BIX-01294 enables neural progenitor cells (NPCs) to be reprogrammed in the absence of exogenous Oct4.
Is this a salt?
Is it cell-permeable?
≥95% by HPLC
DMSO (10 mg/ml) or Ethanol (10 mg/ml)
Maximum time for storage
Protect from air and moisture
For cells, cell lines and tissues in culture till half confluency.
BIX 01294 for activation
BIX 01294 to measure cellular activation