Mouse Monoclonal [clone X75 (3C8/4)] (IgG1) to Human MUC16 / CA125

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Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
About

Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
Test

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin name

Mus musculus

Gene target

Monoclonal X75 3C8/4 IgG1 MUC16 CA125
Gene symbol

MUC16, NBR1
Short name

Mouse Monoclonal [clone X75 (3C8/4)] (IgG1) MUC16 / CA125
Technique

Mouse monoclonal, Mouse, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
Host

mouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
Isotype

IgG1
Species

Human, Humans, Mouses
Alternative name

Mouse monoclonal [clonality X75 (3C8/4)] (IgG1) to H. sapiens mucin 16, cellular surface associated / CA125
Alternative technique

murine
Alternative to gene target

mucin 16, cell surface associated, MUC16 and IDBG-25369 and ENSG00000181143 and 94025, Extracellular, Muc16 and IDBG-136368 and ENSMUSG00000032134 and 73732, MUC16 and IDBG-643029 and ENSBTAG00000037693 and 786607
Clone name

X75

Identity

HGNC:6746
Gene

NBR1
Long gene name

NBR1 autophagy cargo receptor
Synonyms gene
- M17S2
Synonyms gene name
- membrane component, chromosome 17, surface marker 2 (ovarian carcinoma antigen CA125)
- neighbor of BRCA1 gene 1
Synonyms
- CA125
- KIAA0049
- 1A1-3B
GenBank acession
- X76952
Locus

17q21.31
Discovery year

1994-08-29
Entrez gene record

4077
Pubmed identfication
- 8069304
- 26112016
RefSeq identity
- NM_005899
Classification
- Zinc fingers ZZ-type
VEGA ID

OTTHUMG00000180878