ERBB2, phosphorylated (Y1127) (ERBB2, HER2, MLN19, NEU, NGL, Receptor tyrosine-protein kinase erbB-2, Metastatic lymph node gene 19 protein, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Tyrosine kinase-type cell surface receptor HER2, p185erbB2, CD340)

• Catalog number
  MBS6006896
• Price
  Please ask
• Size
  0,2 mL

• Other size
  please contact us to order other different size
• Description
  For cells, cell lines and tissues in culture till half confluency. cDNA genes are a locus (or region) of DNA for functional transcript RNA or protein. An ELISA is used to detect the expressed protein in biological fluids, serum, saliva. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  ERBB2   phosphorylated   Y1127   ERBB2   HER2   MLN19   NEU   NGL   Receptor   tyrosine-protein   kinase   erbB-2   Metastatic   lymph   node   gene   protein   Proto-oncogene   Neu   Proto-oncogene   c-ErbB-2   Tyrosine   kinase   surface   receptor   HER2   p185erbB2   CD340  
• Gene symbol
  ERBB2, NEU1, NEURL1, LRRC4C
• Short name
  ERBB2, phosphorylated (Y1127) (ERBB2, HER2, MLN19, NEU, NGL, Receptor tyrosine-protein kinase erbB-2, Metastatic lymph node 19 protein, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Tyrosine kinase- surface receptor HER2, p185erbB2, CD340)
• Alternative name
  v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian), phosphorylated (Y1127) (v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian), HER2, MLN19, NEU, NGL, Receptor tyrosine-protein phosphorylation catalyst erbB-2, Metastatic lymph node gene 19 protein, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Tyrosine phosphorylation catalyst-classification cellular surface receptor HER2, p185erbB2, CD340)
• Alternative to gene target
  v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian), CD340 and HER-2 and HER-2/neu and HER2 and MLN 19 and NEU and NGL and TKR1, ERBB2 and IDBG-46068 and ENSG00000141736 and 2064, transferase activity, nuclei, Erbb2 and IDBG-210591 and ENSMUSG00000062312 and 13866, ERBB2 and IDBG-639410 and ENSBTAG00000021798 and 505709
• Tissue
  cell, lymph, node

Gene info

• Identity
  HGNC:3430
• Gene
  ERBB2
• Long gene name
  erb-b2 receptor tyrosine kinase 2
• Synonyms gene
  • NGL
• Synonyms gene name
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene homolog)
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
• Synonyms
  • NEU
  • HER-2
  • CD340
  • HER2
• Synonyms name
  • neuro/glioblastoma derived oncogene homolog
  • human epidermal growth factor receptor 2
• GenBank acession
  • X03363
• Locus
  17q12
• Discovery year
  2001-06-22
• Entrez gene record
  2064
• RefSeq identity
  • NM_004448
• Classification
  • Erb-b2 receptor tyrosine kinases
  • CD molecules
  • Minor histocompatibility antigens
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000179300
• Locus Specific Databases
  • LRG_724

Gene info

• Identity
  HGNC:7758
• Gene
  NEU1
• Long gene name
  neuraminidase 1
• Synonyms gene
  • NEU
• Synonyms gene name
  • sialidase 1 (lysosomal sialidase)
  • neuraminidase 1 (lysosomal sialidase)
• GenBank acession
  • AF040958
• Locus
  6p21.33
• Discovery year
  2001-06-22
• Entrez gene record
  4758
• Pubmed identfication
  • 9054950
• Classification
  • Neuraminidases
• VEGA ID
  OTTHUMG00000031284

Gene info

• Identity
  HGNC:7761
• Gene
  NEURL1
• Long gene name
  neuralized E3 ubiquitin protein ligase 1
• Synonyms gene
  • NEURL
• Synonyms gene name
  • neuralized (Drosophila)-like
  • neuralized-like (Drosophila)
  • neuralized homolog (Drosophila)
• Synonyms
  • h-neu
  • RNF67
  • neu-1
• GenBank acession
  • U87864
• Locus
  10q24.33
• Discovery year
  1999-02-09
• Entrez gene record
  9148
• Pubmed identfication
  • 9519875
  • 20847082
• Classification
  • Ring finger proteins
• VEGA ID
  OTTHUMG00000018995

Gene info

• Identity
  HGNC:29317
• Gene
  LRRC4C
• Long gene name
  leucine rich repeat containing 4C
• Synonyms
  • KIAA1580
  • NGL-1
• GenBank acession
  • AB046800
• Locus
  11p12
• Discovery year
  2005-09-13
• Entrez gene record
  57689
• Pubmed identfication
  • 14595443
• RefSeq identity
  • NM_020929
• Classification
  • Ig-like cell adhesion molecule family
  • I-set domain containing
• VEGA ID
  OTTHUMG00000166383

MeSH Data

• Name
  Tumor Stem Cell Assay
• Concept
  Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
• Tree numbers
  • E01.370.225.500.383.910
  • E01.370.225.500.388.930
  • E05.200.500.383.910
  • E05.200.500.388.930
  • E05.242.383.910
  • E05.242.417.500
  • E05.337.550.200.800
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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