anti-Caspase-9 Antibody

  • Catalog number
    2073
  • Price
    Please ask
  • Size
    0.02 mg, 0.1 mg
  • Gene info
    Caspase-9 Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. A novel member in the caspase family was recently identified and designated ICE-LAP6, Mch6, and Apaf-3. Caspase-9 and Apaf-1 bind to each other, which leads to caspase-9 activation. Caspase-9 is also activated by granzyme B and CPP32. Activated caspase-9 cleaves and activates caspase-3 that is one of the key proteases, being responsible for the proteolytic cleavage of many key proteins in apoptosis. Caspase-9 play a central role in cell death induced by a wide variety of apoptosis activators including TNFa;, TRAIL, anti-CD-95, FADD, and TRADD. Caspase-9 is expressed in a variety of human tissues.
  • Gene names
    Caspase-9 Antibody: MCH6, APAF3, APAF-3, PPP1R56, ICE-LAP6, MCH6, Caspase-9, Apoptotic protease Mch-6, CASP-9
  • Antibodie s label
    unlabelled serum
  • Purity
    Caspase-9 Antibody is affinity chromatography purified via peptide column.
  • Ab raised in
    Rabbit
  • Type
    Polyclonal
  • Immunoglobulin
    IgG
  • Spicific to
    Caspase-9 antibody is predicted to have no cross reactivity to other members in the caspase family.
  • Antigen
    Caspase-9 antibody was made against a 20 amino acid peptide near the center of human Caspase-9.
  • Immuno application
    ELISA, Western Blot, immuno-cyto-chemistry, immuno fluorescence, immuno precipitation
  • Antibody advice
    Caspase-9 antibody can be used for detection of caspase-9 by Western blot at 1 ug/mL. Antibody can also be used for immunocytochemistry starting at 2 ug/mL. For immunofluorescence start at 20 ug/mL.
  • Suspention pH azide
    Caspase-9 Antibody is supplied in PBS containing 0.02% sodium azide.
  • Keep at
    Caspase-9 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Works with
    Human
  • Omim nr
    28558771
  • Ncbi nr
    P55211
  • KDa
    Predicted: 46 kDa Observed: 45 kDa
  • Vial with antibody
    in solution
  • Quantity per ml
    1 mg/mL
  • NCBI GENE nr
    842
  • GENE symbol
    CASP9
  • Antigene name
    caspase 9, apoptosis-related cysteine peptidase
  • Source
    Homo sapiens
  • Protein nr
    P55211
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
  • Properties
    If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
  • Gene symbol
    CARD9, CASP9, CARD19
  • Short name
    anti-Caspase-9 Antibody
  • Technique
    Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
  • Alternative name
    Antibody toCasp-9 (antibody to-)
  • Alternative technique
    antibodies
Gene info
  • Identity
  • Gene
  • Long gene name
    caspase recruitment domain family member 9
  • Synonyms gene name
    • caspase recruitment domain family, member 9
  • GenBank acession
  • Locus
  • Discovery year
    2001-08-13
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Caspase recruitment domain containing
  • VEGA ID
  • Locus Specific Databases
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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