H3B-6527

  • Catalog number
    B1647-25
  • Price
    Please ask
  • Size
    25 mg
  • Alternative_name
    H3B-6527, H3B 6527; H3B6527; N-{2-[(6-{[(2,6-Dichloro-3,5-dimethoxyphenyl)carbamoyl](methyl)amino}-4-pyrimidinyl)amino]-5-(4-ethyl-1-piperazinyl)phenyl}acrylamide
  • Description
    H3B-6527 is an orally bioavailable inhibitor of human fibroblast growth factor receptor 4 (FGFR4), with potential antineoplastic activity.
  • CAS Number
    1702259-66-2
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₉H₃₄Cl₂N₈O₄
  • Molecular Weight
    629.54
  • Cell Permeable
    Yes
  • Purity
    >98%
  • Solubilities
    DMSO
  • Handling
    Protect from air and light
  • Tag Line
    A highly selective FGFR4 inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • MDL Number
    NA
  • PubChem CID
    118029202
  • SMILES
    CCN1CCN(CC1)C2=CC(=C(C=C2)NC3=CC(=NC=N3)N(C)C(=O)NC4=C(C(=CC(=C4Cl)OC)OC)Cl)NC(=O)C=C
  • InChi
    InChI=1S/C29H34Cl2N8O4/c1-6-25(40)35-20-14-18(39-12-10-38(7-2)11-13-39)8-9-19(20)34-23-16-24(33-17-32-23)37(3)29(41)36-28-26(30)21(42-4)15-22(43-5)27(28)31/h6,8-9,14-17H,1,7,10-13H2,2-5H3,(H,35,40)(H,36,41)(H,32,33,34)
  • InChi Key
    MBWRLLRCTIYXDW-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    H3B-6527
  • Alternative name
    H3B-6527
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