H3B-6527
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Catalog numberB1647-5
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PricePlease ask
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Size5 mg
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Alternative_nameH3B-6527, H3B 6527; H3B6527; N-{2-[(6-{[(2,6-Dichloro-3,5-dimethoxyphenyl)carbamoyl](methyl)amino}-4-pyrimidinyl)amino]-5-(4-ethyl-1-piperazinyl)phenyl}acrylamide
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DescriptionH3B-6527 is an orally bioavailable inhibitor of human fibroblast growth factor receptor 4 (FGFR4), with potential antineoplastic activity.
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CAS Number1702259-66-2
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₉H₃₄Cl₂N₈O₄
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Molecular Weight629.54
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Cell PermeableYes
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Purity>98%
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SolubilitiesDMSO
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HandlingProtect from air and light
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Tag LineA highly selective FGFR4 inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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MDL NumberNA
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PubChem CID118029202
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SMILESCCN1CCN(CC1)C2=CC(=C(C=C2)NC3=CC(=NC=N3)N(C)C(=O)NC4=C(C(=CC(=C4Cl)OC)OC)Cl)NC(=O)C=C
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InChiInChI=1S/C29H34Cl2N8O4/c1-6-25(40)35-20-14-18(39-12-10-38(7-2)11-13-39)8-9-19(20)34-23-16-24(33-17-32-23)37(3)29(41)36-28-26(30)21(42-4)15-22(43-5)27(28)31/h6,8-9,14-17H,1,7,10-13H2,2-5H3,(H,35,40)(H,36,41)(H,32,33,34)
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InChi KeyMBWRLLRCTIYXDW-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameH3B-6527
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Alternative nameH3B-6527
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