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PU H71 for cell activation

PU H71 for cell activation is available 2 times from Biovision labs

9649-10 | PU-H71 for cell activation size: 10 mg | 198.56 USD

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9649-50 | PU-H71 for cell activation size: 50 mg | 618.36 USD

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Other name 6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine
Supplied with N/A
Description PU-H71 is a potent Heat Shock Protein 90 (Hsp90) inhibitor (IC₅₀ = 50 nM). Also inhibits cell growth in a range of breast cancer cell lines (IC₅₀ values are 17, 31, 65, 87 and 140 nM for SKBr3, MCF-7, MDA-MB-468, HCC-1806 and MDA-MB-231 cells respectively). Shown to inhibit cell proliferation and induce apoptosis in triple-negative breast cancer (TNBC) cells.
Category Biochemicals
Molecular formula C₁₈H₂₁IN₆O₂S
Is it cell-permeable? Yes
Molecular weight 512.37
Storage condition -20°C
Shipping condition gel pack
Purification ≥98% by HPLC
Peptide sequence N/A
Is this a salt? No
CAS number 873436-91-0
Storage instructions Protect from air and light
Maximum time for storage 36 months
Physical appearance Off-white solid
Reconstitute instructions DMSO (>40 mg/ml)
Additional description For cells, cell lines and tissues in culture till half confluency.
Gene targetPU-H71 for activation
Short name PU-H71 for activation
Technique activation
Alternative name PU-H71 to measure cellular activation
Tissue cell
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