ACHE Antibody (NT)

  • Catalog number
    6706-100
  • Price
    Please ask
  • Size
    100 μl
  • Antibody Target
    ACHE
  • Target Alternative Name
    ACHE; Acetylcholinesterase
  • Antibody Type
    Polyclonal
  • Species Reactivities
    Human
  • Immunogen Sequence
    This ACHE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-175 amino acids from the N-terminal region of human ACHE.
  • Accession
    P22303
  • Gene Id
    ACHE
  • Appearance
    Colorless liquid
  • Form
    Liquid
  • Formulation
    100 µl of antibody in PBS with 0.09% (W/V) sodium azide
  • Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
  • Application
    Western blot, IHC, IF, FACS
  • Positive Control
    Western blot: Jurkat, Raji and Y79 cell lysate, IHC: human brain tissue, IF: NCI-H460 cells, FACS: NCI-H460 cells
  • Application And Usages
    Western blot: ~1:1000, FACS: ~1:10–1:50, IHC: ~1:10-1:50, IF: 1:10-1:50.
  • Description
    Acetylcholinesterase (AChE) hydrolyzes acetylcholine at synaptic junctions. Alternative mRNA splicing gives rise to three forms of AChE. It plays a role in neuronal apoptosis. The T form, also known as the asymmetric form, is soluble and is present in synapses. The H form is also known as the globular form and is present on the outer surfaces of cell membranes. The R form is not known to be a functional species. AChE globular form subunits are GPI-anchored to cell membranes and asymmetric subunits are anchored to basal lamina components by a collagen tail. The catalytic subunits of AChE are oligomers composed of disulfide-linked homodimers. The loss of AChE from cholinergic and noncholinergic neurons in the brain is seen in patients with Alzheimer’s disease. However, AChE activity is increased around amyloid plaques, which may be due to a disturbance in calcium homeostasis involving the opening of L-type voltage-dependent calcium channels.
  • Storage Condition
    -20 °C
  • Shipping Condition
    gel pack
  • Shelf Life
    12 months
  • Usage
    For Research Use Only! Not to be used in humans.
  • Handling
    The antibody solution should be gently mixed before use.
  • Western Blot Verified
    Verified
  • Immunocytochemistry Verified
    Verified
  • Immunofluorescence Verified
    Verified
  • Immunoprecipitation Verified
    Not Verified
  • ELISA Verified
    Not Verified
  • ChIP Verified
    Not Verified
  • Flow Cytometry Verified
    Verified
  • Properties
    If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    ACHE  
  • Gene symbol
    ACHE
  • Short name
    ACHE Antibody (NT)
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Rabbit IgG
  • Alternative name
    acetylcholinesterase (antibody to-) (NT)
  • Alternative technique
    antibodies
  • Alternative to gene target
    acetylcholinesterase, ACEE and ARACHE and N-ACHE and YT, ACHE and IDBG-32513 and ENSG00000087085 and 43, protein self-association, nuclei, Ache and IDBG-204838 and ENSMUSG00000023328 and 11423, ACHE and IDBG-640435 and ENSBTAG00000001139 and 540446
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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