anti-FGA Antibody

• Catalog number
  25-722
• Price
  Please ask
• Size
  50 ug

• Gene info
  FGA is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in its gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus.
• Gene names
  FGA, Fib2, MGC119422, MGC119423, MGC119425
• Antibodie s label
  unlabelled serum
• Purity
  Antibody is purified by peptide affinity chromatography method.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Antigen
  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FGA.
• Immuno application
  ELISA, Western Blot
• Antibody advice
  FGA antibody can be used for detection of FGA by ELISA at 1:12500. FGA antibody can be used for detection of FGA by western blot at 1 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
• Suspention pH azide
  Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
• Keep at
  For short periods of storage (days) store at 4 grades C. For longer periods of storage, store FGA antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
• Works with
  Human
• Omim nr
  11761629
• Ncbi nr
  NP_068657
• KDa
  66 kDa
• Vial with antibody
  Lyophilized
• Quantity per ml
  1 mg/ml
• NCBI GENE nr
  2243
• GENE symbol
  FGA
• Antigene name
  fibrinogen alpha chain
• Source
  Homo sapiens
• Protein nr
  Q4QQH7
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  FGA  
• Gene symbol
  FGA
• Short name
  anti-FGA Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toFGA (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  fibrinogen alpha chain, Fib2, FGA and IDBG-42099 and ENSG00000171560 and 2243, protein binding, Extracellular, Fga and IDBG-154534 and ENSMUSG00000028001 and 14161, FGA and IDBG-628958 and ENSBTAG00000001638 and 522039

Gene info

• Identity
  HGNC:3661
• Gene
  FGA
• Long gene name
  fibrinogen alpha chain
• Synonyms gene name
  • fibrinogen, A alpha polypeptide
• Locus
  4q31.3
• Discovery year
  2001-06-22
• Entrez gene record
  2243
• RefSeq identity
  • NM_000508
• Classification
  • Fibrinogen C domain containing
  • Receptor ligands
• VEGA ID
  OTTHUMG00000150330
• Locus Specific Databases
  • LRG_557

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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