Bax (Apoptosis Marker) Mouse Monoclonal Antibody

  • Catalog number
    MBS438080
  • Price
    Please ask
  • Size
    0.1 mg (Without BSA & Azide at 1mg/mL)
  • Products_type
    Antibody
  • Products_short_name
    [Bax]
  • Products_name_syn
    [Apoptosis regulator BAX cytoplasmic isoform beta, Apoptosis regulator BAX membrane isoform alpha, Bax isoform psi, Bax protein cytoplasmic isoform delta, Bax protein cytoplasmic isoform gamma, Bax zeta, Bcl-2-like protein 4, BCL2 associated X protein, BCL2 associated X protein omega, BCL2 associated X protein transcript variant delta2, BCL2L4]
  • Other_names
    [apoptosis regulator BAX isoform 1; Apoptosis regulator BAX; apoptosis regulator BAX; BCL2 associated X, apoptosis regulator; Bcl-2-like protein 4; Bcl2-L-4]
  • Products_gene_name
    [BAX]
  • Other_gene_names
    [BAX; BAX; BCL2L4; BCL2L4; Bcl2-L-4]
  • Clonality
    Monoclonal
  • Clone
    [SPM336]
  • Reactivity
    Human, Monkey. Does not react with Mouse and Rat
  • Specificity
    Recognizes a protein of 21kDa, identified as the Bax protein. This MAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.
  • Form
    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
  • Storage_stability
    Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
  • Tested_application
    Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC) Formalin
  • Properties
    If you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Description
    This 1 is suited for programmed cell-death studies.
  • About
    Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
  • Test
    Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
  • Latin name
    Mus musculus
  • French translation
    anticorps
  • Gene target
    Bax   Monoclonal  
  • Short name
    Bax (Apoptosis ) Mouse Monoclonal Antibody
  • Technique
    Mouse monoclonal, apoptosis, Antibody, Mouse, antibodies against human proteins, antibodies for, apoptosis pathway, Component cell markers and DNA bp. markers are genetic markers er genes or DNA sequences with a known location on a chromosome that can be used to identify individuals or species. Protein markers in kDA. Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
  • Host
    Mouse, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
  • Isotype
    IgG1
  • Species
    Mouse, Mouses
  • Alternative name
    BCL2-associated X protein (programmed cellular destruction detection labelled) Mouse monoclonal (antibody to-)
  • Alternative technique
    celldeath, antibodies, murine
  • Alternative to gene target
    BCL2-associated X protein, BCL2L4, BAX and IDBG-61459 and ENSG00000087088 and 581, BH3 domain binding, nuclei, Bax and IDBG-183241 and ENSMUSG00000003873 and 12028, BAX and IDBG-640344 and ENSBTAG00000013340 and 100850136,280730
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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