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Human CSF2RA CRISPR Knock Out Cell Line

Human CSF2RA CRISPR Knock Out Cell Line is available 9 times from Abm crispr labs

K0515152 | Human CSF2RA CRISPR Knock Out 293 Cell Line size: 1x10^6 cells/1.0ml | 6,651.66 USD

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K0515151 | Human CSF2RA CRISPR Knock Out 293T Cell Line size: 1x10^6 cells/1.0ml | 6,651.66 USD

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K0515153 | Human CSF2RA CRISPR Knock Out A549 Cell Line size: 1x10^6 cells/1.0ml | 6,651.66 USD

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K0515154 | Human CSF2RA CRISPR Knock Out HeLa Cell Line size: 1x10^6 cells/1.0ml | 6,651.66 USD

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K0515156 | Human CSF2RA CRISPR Knock Out HepG2 Cell Line size: 1x10^6 cells/1.0ml | 6,651.66 USD

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K0515158 | Human CSF2RA CRISPR Knock Out K562 Cell Line size: 1x10^6 cells/1.0ml | 6,651.66 USD

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K0515157 | Human CSF2RA CRISPR Knock Out MCF7 Cell Line size: 1x10^6 cells/1.0ml | 6,651.66 USD

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K0515155 | Human CSF2RA CRISPR Knock Out MDA-MB-435 Cell Line size: 1x10^6 cells/1.0ml | 6,651.66 USD

Catalog number K0515155
Supplier ABM CrispR
Price6,651.66 USD
Size 1x10^6 cells/1.0ml
Cell line type MDA-MB-435
Ordering If you wish to order this product, please include the catalogue number #K0515155in your purchase order among with your shipping and billing information.
Short name CSF2RA CRISPR Knock Out MDA-MB-435 Line
Alternative name H. sapiens colony stimulating factor 2 receptor, a, low-affinity (granulocyte-macrophage) CRISPR Knock Out MDA-myoglobin-435 cellular Line
Alternative to gene target myoglobin, myoglobgin and PVALB, MB and IDBG-5491 and ENSG00000198125 and 4151, heme binding, multiple, Mb and IDBG-157509 and ENSMUSG00000018893 and 17189, MB and IDBG-637940 and ENSBTAG00000005333 and 280695, colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage), CD116 and CDw116 and CSF2R and CSF2RAX and CSF2RAY and CSF2RX and CSF2RY and GM-CSF-R-alpha and GMCSFR and GMR and SMDP4, CSF2RA and IDBG-39400 and ENSG00000198223 and 102725415,1438, protein binding, Extracellular, Csf2ra and IDBG-182098 and ENSMUSG00000059326 and 12982, CSF2RA and IDBG-642291 and ENSBTAG00000045948 and 100336606,511847
1. Gene info
Identity6915
GeneMB
Long gene name myoglobin
Synonyms
Locus22q12.3
Discovery year 2001-06-22
Entrez gene record4151
Pubmed identfication
RefSeq identity
Havana BLAST/BLATOTTHUMG00000150606
2. Gene info
Identity2435
GeneCSF2RA
Long gene name colony stimulating factor 2 receptor alpha subunit
Synonyms gene
Synonyms gene name
  • colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
GenBank acession
Discovery year 1990-07-03
Entrez gene record1438
Pubmed identfication
Classification
  • CD molecules
  • Pseudoautosomal region 1
Havana BLAST/BLATOTTHUMG00000012533
Locus Specific Databases
Additional information
PubMedreceptors alphaGMR and c-Kit could interact to coordinate their signal initiation; alphaGMR inhibited c-Kit auto-phosphorylation induced by the ligand stem cell factor
soluble forms of the GM-CSF receptor alpha chain and beta chain were produced and a novel mechanism of receptor assembly was demonstrated
Analysis of the 5' promoter of the GM-CSF receptor alpha gene.
Results highlight the importance of GM-CSFR expression in monocytes for cytokine-induced myeloid dendritic cells (DC) generation and point to GM-CSF as a direct player in the generation of functionally distinct DC.
These results establish that GM-CSF signaling is critical for surfactant homeostasis in humans and demonstrate that mutations in CSF2RA cause familial PAP.
Observational study of gene-disease association. (HuGE Navigator)
Identify defective expression and function of CD116 as a distinguishing feature of IBD and implicate an associated defect in innate immune responses toward granulocyte-macrophage colony-stimulating factor.
The GM-CSF Ralpha were ubiquitously but not uniformly expressed in neurons throughout the brain and downregulation in brain in patient with alzheimenr disease.
This study reveals a novel functional role of clathrin-coated structure in GMR signaling and the oncogenesis of JAK2V617F.
A possible relationship between dysfunction of the granulocyte-macrophage colony stimulating factor receptor, mapping to the pseudoautosomal X-Y region, may exist in myelodysplastic patients with initially lymphocytic Sweet syndrome.
Product images
    #Human#.jpg

K0515159 | Human CSF2RA CRISPR Knock Out U87-MG Cell Line size: 1x10^6 cells/1.0ml | 6,651.66 USD

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Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
NCBI number NM_006140
Technical file Please contact us to request the latest datasheet, protocol, certificate of analysis and SDS files.
Notes Designed for Research Use Only. Manufactured in Canada.
Description For cells, cell lines and tissues in culture till half confluency.
Properties Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Species Human
Tissue cell
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