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Human CSF2RA CRISPR Knock Out Cell Line

Human CSF2RA CRISPR Knock Out Cell Line is available 9 times from Abm crispr labs

K0515152 | Human CSF2RA CRISPR Knock Out 293 Cell Line size: 1x10^6 cells/1.0ml | 6,604.51 USD

Catalog number K0515152
Supplier ABM CrispR
Price6,604.51 USD
Size 1x10^6 cells/1.0ml
Cell line type 293
Ordering If you wish to order this product, please include the catalogue number #K0515152in your purchase order among with your shipping and billing information.
Short name CSF2RA CRISPR Knock Out 293 Line
Alternative name H. sapiens colony stimulating factor 2 receptor, a, low-affinity (granulocyte-macrophage) CRISPR Knock Out 293 cellular Line
Alternative to gene target colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage), CD116 and CDw116 and CSF2R and CSF2RAX and CSF2RAY and CSF2RX and CSF2RY and GM-CSF-R-alpha and GMCSFR and GMR and SMDP4, CSF2RA and IDBG-39400 and ENSG00000198223 and 102725415,1438, protein binding, Extracellular, Csf2ra and IDBG-182098 and ENSMUSG00000059326 and 12982, CSF2RA and IDBG-642291 and ENSBTAG00000045948 and 100336606,511847
1. Gene info
Identity2435
GeneCSF2RA
Long gene name colony stimulating factor 2 receptor alpha subunit
Synonyms gene
Synonyms gene name
  • colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
GenBank acession
Discovery year 1990-07-03
Entrez gene record1438
Pubmed identfication
Classification
  • CD molecules
  • Pseudoautosomal region 1
Havana BLAST/BLATOTTHUMG00000012533
Locus Specific Databases
Additional information
PubMedfunctional studies demonstrated GMCSF-dependent activation of IkappaB kinase activity in endothelial cells, degradation of IkappaB, and activation of NF-kappaB
receptors alphaGMR and c-Kit could interact to coordinate their signal initiation; alphaGMR inhibited c-Kit auto-phosphorylation induced by the ligand stem cell factor
soluble forms of the GM-CSF receptor alpha chain and beta chain were produced and a novel mechanism of receptor assembly was demonstrated
Constitutive secretion of soluble GMR alpha by monocytes (but not lymphocytes) is up-regulated by GM-CSF and inflammatory mediators in a protein form that represents a mixed population of alternatively spliced and proteolytically cleaved species.
The novel GMRalpha transcript identified herein contains a previously undescribed exon of the GMRalpha gene; this exon derives from an Alu DNA repeat element
Results highlight the importance of GM-CSFR expression in monocytes for cytokine-induced myeloid dendritic cells (DC) generation and point to GM-CSF as a direct player in the generation of functionally distinct DC.
best diffracting crystals of ternary complex were obtained using the N346Q mutation of the betac subunit. Crystals grew using polyethylene glycol 3350 with a high concentration of proline, belonged to space group P6(3)22 and diffracted to 3.3 A resolution
Results suggest that that pulmonary alveolar proteinosis can result from a genetic deficiency of the GM-CSF receptor alpha chain, encoded in the X-chromosome pseudoautosomal region 1.
The expression rate of GM-CSFR in myelodysplastic syndrome patients was significantly higher than in aplastic anemia patients and controls.
regulatory molecule causative of aortic dissection and intramural haematoma
Product images
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K0515151 | Human CSF2RA CRISPR Knock Out 293T Cell Line size: 1x10^6 cells/1.0ml | 6,604.51 USD

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K0515153 | Human CSF2RA CRISPR Knock Out A549 Cell Line size: 1x10^6 cells/1.0ml | 6,604.51 USD

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K0515154 | Human CSF2RA CRISPR Knock Out HeLa Cell Line size: 1x10^6 cells/1.0ml | 6,604.51 USD

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K0515156 | Human CSF2RA CRISPR Knock Out HepG2 Cell Line size: 1x10^6 cells/1.0ml | 6,604.51 USD

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K0515158 | Human CSF2RA CRISPR Knock Out K562 Cell Line size: 1x10^6 cells/1.0ml | 6,604.51 USD

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K0515157 | Human CSF2RA CRISPR Knock Out MCF7 Cell Line size: 1x10^6 cells/1.0ml | 6,604.51 USD

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K0515155 | Human CSF2RA CRISPR Knock Out MDA-MB-435 Cell Line size: 1x10^6 cells/1.0ml | 6,604.51 USD

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K0515159 | Human CSF2RA CRISPR Knock Out U87-MG Cell Line size: 1x10^6 cells/1.0ml | 6,604.51 USD

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Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
NCBI number NM_006140
Technical file Please contact us to request the latest datasheet, protocol, certificate of analysis and SDS files.
Notes Designed for Research Use Only. Manufactured in Canada.
Description For cells, cell lines and tissues in culture till half confluency.
Properties Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Species Human
Tissue cell
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