RO 20-1724
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Catalog number2042-250
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PricePlease ask
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Size250 mg
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Alternative_name4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone
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DescriptionCell-permeable. A potent,selective, cAMP-specific phosphodiesterase inhibitor (PDE IV, IC50 = 2 µM). Inhibits superoxide generation and platelet aggregation stimulated by arachidonic acid. Also inhibits fMLP-induced neutrophil adhesion to vascular endothelial cells.
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CAS Number29925-17-5
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₁₅H₂₂N₂O₃
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Molecular Weight278.35
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Cell PermeableYes
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Purity≥99% by TLC
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SolubilitiesDMSO (~200 mg/ml) or Ethanol (~40 mg/ml)
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HandlingProtect from air and light
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Tag LineA potent PDEIV inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life24 months
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MDL NumberMFCD00077397
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PubChem CID5087
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SMILESCCCCOC1=C(C=CC(=C1)CC2CNC(=O)N2)OC
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InChiInChI=1S/C15H22N2O3/c1-3-4-7-20-14-9-11(5-6-13(14)19-2)8-12-10-16-15(18)17-12/h5-6,9,12H,3-4,7-8,10H2,1-2H3,(H2,16,17,18)
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InChi KeyPDMUULPVBYQBBK-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Gene symbolPIRC104, PIRC103, SNORD115-20, SNORD114-20, SNORD116-20, IGKV3-20, IGLVI-20
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Short nameRO 20-1724
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Alternative nameRO 20-1724
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Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 104
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters
Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 103
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters
Gene info
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Identity
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Gene
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Long gene namesmall nucleolar RNA, C/D box 115-20
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Synonyms
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GenBank acession
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Locus
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Discovery year2007-02-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small nucleolar RNAs, C/D box
Gene info
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Identity
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Gene
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Long gene namesmall nucleolar RNA, C/D box 114-20
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Synonyms
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Locus
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Discovery year2006-09-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small nucleolar RNAs, C/D box
Gene info
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Identity
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Gene
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Long gene namesmall nucleolar RNA, C/D box 116-20
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Synonyms
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GenBank acession
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Locus
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Discovery year2007-02-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small nucleolar RNAs, C/D box
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin kappa variable 3-20
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GenBank acession
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Locus
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Discovery year2000-04-18
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin kappa locus at 2p11.2
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin lambda variable (I)-20 (pseudogene)
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Synonyms gene name
- immunoglobulin lambda variable (I)-20
- immunoglobulin lambda variable (I)-20 pseudogene
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-05-08
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin lambda locus at 22q11.2
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VEGA ID