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Products_type
Active Protein
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Products_short_name
[CD11c]
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Products_name_syn
[CD11c, Recombinant, Human (Monocyte/Macrophage, CD11 Antigen-like Family Member C, Complement Component 3 Receptor 4 Subunit, Integrin alphaX, ITGAX, ITAX, Leukocyte Adhesion Glycoprotein p150,95 alpha Chain, Leukocyte Adhesion Receptor p150,95, Leu M5, L]
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Other_names
[CD83 antigen isoform c; CD83 antigen; CD83 antigen; hCD83; B-cell activation protein; cell surface protein HB15; cell-surface glycoprotein; CD83 antigen (activated B lymphocytes, immunoglobulin superfamily); CD83 molecule; B-cell activation protein; Cell surface protein HB15]
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Other_gene_names
[CD83; CD83; BL11; HB15; hCD83]
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Purity
Purified95% (SDSPAGE)
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Form
Supplied as a lyophilized powder from 0.2um filtered solution in PBS. Reconstitute with sterile 200ug/ml PBS.
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Storage_stability
Lyophilized powder may be stored at -20 degree C. Reconstitute with sterile buffer or ddH2O. Aliquot and store at -20 degree C. Reconstituted product is stable for 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Description
cell adhesion molecules play a role in cell growth and activation and are often identified by WB or ELISA as in the CD11c, Recombinant, (Monocyte/Macrophage, CD11 Antigen-like Family Member C, Complement Component 3 Receptor 4 Subunit, Integrin alphaX, ITGAX, ITAX, Leukocyte Adhesion Glycoprotein p150 95 alpha Chain, Leukocyte Adhesion Receptor p150 95, Leu M5, L. The CD11c, Recombinant, (Monocyte/Macrophage, CD11 Antigen-like Family Member C, Complement Component 3 Receptor 4 Subunit, Integrin alphaX, ITGAX, ITAX, Leukocyte Adhesion Glycoprotein p150 95 alpha Chain, Leukocyte Adhesion Receptor p150 95, Leu M5, L is a α- or alpha protein sometimes glycoprotein present in blood. Antigens are peptides or recombinant or native dependent on the production method. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
ITGAX
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Short name
CD11c, Recombinant, (Monocyte/Macrophage, CD11 Antigen-like Family Member C, Complement Component 3 Receptor 4 Subunit, Integrin alphaX, ITGAX, ITAX, Leukocyte Adhesion Glycoprotein p150 95 alpha Chain, Leukocyte Adhesion Receptor p150 95, Leu M5, L
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Technique
Recombinant, antigen, antigenes, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Species
Human, Humans
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Alternative name
CD11c, Rec., H. sapiens (Monocyte/Macrophage, CD11 protein-like family Member C, Complement Component 3 Receptor 4 functionnal sequence, Integrin alphaX, integrin, alpha X (complement component 3 receptor 4 subunit), ITAX, Leukocyte Adhesion Glycoprotein p150,95 a epitope, Leukocyte Adhesion Receptor p150,95, L-leucine M5, L
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Alternative technique
rec, antigenes
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Alternative to gene target
integrin, alpha X (complement component 3 receptor 4 subunit), CD11C and SLEB6, ITGAX and IDBG-28212 and ENSG00000140678 and 3687, metal ion binding, Cell surfaces, Itgax and IDBG-210550 and ENSMUSG00000030789 and 16411
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