CXCR6 Antibody
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Catalog numberR31193
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PricePlease ask
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Size0.1mg
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CategoryAntibody
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Concentration0.5mg/ml if reconstituted with 0.2ml sterile DI water
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FormAntigen affinity purified
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ConjugationUnconjugated
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ClonePolyclonal antibody
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Recognised antigenCXCR6
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Host animalRabbit (Oryctolagus cuniculus)
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ClonalityPolyclonal (rabbit origin)
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Species reactivityHuman (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applicationsWB, IHC-P
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Recommended dilutionsWestern blot: 0.5-1ug/ml,IHC (Paraffin): 0.5-1ug/ml
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NotesThe stated application concentrations are suggested starting amounts. Titration of the CXCR6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Intented useThis CXCR6 antibodyis to be used only for research purposes and not for diagnostics..
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UniprotO00574
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PurityAntigen affinity
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DescriptionChemokine CXC Motif Receptor 6, also known as STRL33 and Bonzo, is a protein that in humans is encoded by the CXCR6 gene. By Southern blot analysis of genomic DNA and somatic cell hybrid analysis, Liao et al.(1997) mapped the single-copy gene to chromosome 3. Matloubian et al.(2000) found that human and mouse cells expressing the protein showed a strong chemotactic response to CXCL16 but not to other chemokines. The authors concluded that CXCL16 and CXCR6 most likely function in interactions between dendritic cells and T cells and in regulating T-cell migration in the splenic red pulp. Kim et al.(2001) concluded that the proteinb may be important in the trafficking of effector T cells mediating type-1 inflammation.
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ImmunogenAn amino acid sequence from the C-terminus of human Chemokine CXC Motif Receptor 6 (EDNSKTFSASHNVEATSMFQL) was used as the immunogen for this CXCR6 antibody.
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StorageAfter reconstitution, the CXCR6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
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PropertiesIf you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolCXCR6
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Short nameAnti-CXCR6
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative nameAntibodies to CXCR6
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Alternative techniqueantibodies
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Alternative to gene targetchemokine (C-X-C motif) receptor 6, BONZO and CD186 and STRL33 and TYMSTR, CXCR6 and IDBG-29993 and ENSG00000172215 and 10663, C-X-C chemokine receptor activity, Plasma membranes, Cxcr6 and IDBG-206490 and ENSMUSG00000048521 and 80901, CXCR6 and IDBG-646261 and ENSBTAG00000015708 and 506807
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Gene info
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Identity
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Gene
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Long gene nameC-X-C motif chemokine receptor 6
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Synonyms gene name
- chemokine (C-X-C motif) receptor 6
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-08-23
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Entrez gene record
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Pubmed identfication
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Classification
- C-X-C motif chemokine receptors
- CD molecules
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data