FGA Antibody
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Catalog numberA00816-1
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PricePlease ask
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Size0,1 mg
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Target antigenFGA
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ClonalityPolyclonal antibody
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ClonePolyclonal antibody
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Raised inrabbit
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Type of the antibodyIgG polyclonal antibody
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Product formfreeze-dried
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Reacts with specieshuman
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AnalysesWB
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ImmunogenA synthetic peptide corresponding to a sequence at the C-terminus of human FGA (687-727aa RTWQDYKRGFGSLNDEGEGEFWLGNDYLHLLTQRGSVLRVE), different from the related mouse and rat sequences by two amino acids.
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Product configurationEach vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
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PurificationImmunogen affinity purified.
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SolubilizationThe powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
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Storage condtionsKeep the FGA Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
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TipsThe FGA Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
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BackgroundFibrinogen alpha chain is a protein that in humans is encoded by the FGA gene. This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by thrombin during the conversion of fibrinogen to fibrin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing.
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Related articles1. "Entrez Gene: FGA fibrinogen alpha chain". 2. Herrick S, Blanc-Brude O, Gray A, Laurent G (Jul 1999). "Fibrinogen". The International Journal of Biochemistry & Cell Biology. 31 (7): 741–746. 3. Tsurupa G, Medved L (Jan 2001). "Identification and characterization of novel tPA- and plasminogen-binding sites within fibrin(ogen) alpha C-domains". Biochemistry. 40 (3): 801–808.
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Gene NameFGA
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Protein NameFibrinogen alpha chain
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Gene Full Namefibrinogen alpha chain
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SynonymsAc1873 | Fba5e | FGA | Fibrinopeptide A | Fib2 | P02671
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Uniprot IDP02671
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Entrez GeneID2243
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PropertiesIf you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolFGA
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Short nameFGA Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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Alternative namefibrinogen alpha chain (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targetfibrinogen alpha chain, Fib2, FGA and IDBG-42099 and ENSG00000171560 and 2243, protein binding, Extracellular, Fga and IDBG-154534 and ENSMUSG00000028001 and 14161, FGA and IDBG-628958 and ENSBTAG00000001638 and 522039
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Gene info
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Identity
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Gene
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Long gene namefibrinogen alpha chain
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Synonyms gene name
- fibrinogen, A alpha polypeptide
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Locus
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Discovery year2001-06-22
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Entrez gene record
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RefSeq identity
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Classification
- Fibrinogen C domain containing
- Receptor ligands
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data