Target of this antibody:
Alternative names of antibody target:
Urokinase plasminogen activator receptor , PLAUR , uPAR , CD87 , MO3 , UPAR , URKR, Urokinase plasminogen activator surface receptor; U-PAR; uPAR; Monocyte activation antigen Mo3; CD_antigen, CD87
Shelf time: 12 months in temp.: -20 deg.C
How to handle this antibody:
The antibody solution should be gently mixed before use.
uPAR (Urokinase plasminogen activator receptor) is a 55 kDa glycoprotein I-anchored surface receptor specific for urokinase plasminogen activator (uPA). Upon binding to uPAR, uPA converts the surface bound, large serum β-globulin, plasminogen to plasmin. Plasmin, which is also designated fibrinolysin, is a trypsin-like enzyme that acts on Arg-Lys bonds and induces pericellular proteolysis in fibrin and fibrinogen, and thereby contributes to the systematic activation of the coagulation cascade. uPA and uPAR are known to be overexpressed in mesenchymal and epithelial tumor cells and are required for tumor invasion and metastasis.
Clonality of antibody:
Form of antibody:
Concentration of antibody:
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
antibody to-uPAR (Antibody to)