uPAR Antibody

• Catalog number
  3722-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  uPAR
• Target Alternative Name
  Urokinase plasminogen activator receptor , PLAUR , uPAR , CD87 , MO3 , UPAR , URKR, Urokinase plasminogen activator surface receptor; U-PAR; uPAR; Monocyte activation antigen Mo3; CD_antigen, CD87
• Antibody Type
  Polyclonal
• Species Reactivities
  Rat
• Immunogen Sequence
  Synthetic peptide surrounding amino acid 51 of rat uPAR
• Accession
  P49616
• Gene Id
  50692
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in 1X phosphate-buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA and 0.01% thimerosal.
• Purification
  Affinity purified
• Application
  Western blot
• Application And Usages
  Western blotting (0.5-1 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes 33 kDa rat uPAR. Reactivity to other species has not been tested.
• Description
  uPAR (Urokinase plasminogen activator receptor) is a 55 kDa glycoprotein I-anchored surface receptor specific for urokinase plasminogen activator (uPA). Upon binding to uPAR, uPA converts the surface bound, large serum β-globulin, plasminogen to plasmin. Plasmin, which is also designated fibrinolysin, is a trypsin-like enzyme that acts on Arg-Lys bonds and induces pericellular proteolysis in fibrin and fibrinogen, and thereby contributes to the systematic activation of the coagulation cascade. uPA and uPAR are known to be overexpressed in mesenchymal and epithelial tumor cells and are required for tumor invasion and metastasis.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  uPAR  
• Gene symbol
  PLAUR, NCRUPAR
• Short name
  uPAR Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  uPAR (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:9053
• Gene
  PLAUR
• Long gene name
  plasminogen activator, urokinase receptor
• Synonyms
  • URKR
  • UPAR
  • CD87
• Synonyms name
  • urokinase-type plasminogen activator (uPA) receptor
  • urokinase plasminogen activator surface receptor
• Locus
  19q13
• Discovery year
  1991-06-05
• Entrez gene record
  5329
• RefSeq identity
  • NM_002659
• Classification
  • LY6/PLAUR domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000182778
• Locus Specific Databases
  • LRG_637

Gene info

• Identity
  HGNC:37153
• Gene
  NCRUPAR
• Long gene name
  non-protein coding RNA, upstream of F2R/PAR1
• Synonyms
  • ncR-uPAR
  • NCRNA00193
• Synonyms name
  • noncoding RNA upstream of the PAR-1
  • non-protein coding RNA 193
• Locus
  5q13.3
• Discovery year
  2009-07-29
• Entrez gene record
  100302746
• Pubmed identfication
  • 12084570
• RefSeq identity
  • NR_028375
• Classification
  • Long non-coding RNAs with non-systematic symbols

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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