Cardio Trombophilia Panel Real Time PCR kit for detection of 8 mutations: F2 20210 G>A, F5 1691 G>A (Arg506Gln), F710976 G>A (Arg353Gln), F13 G>T (Val34Leu), FGB -455 G>A, ITGA2 807 C>T (Phe224Phe), ITGB3 1565 T>C(Leu33Pro), SERPINE1(PAI1) -675 5G>4G
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Catalog number
R1/P-48FRT SA
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Price
Please ask
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Size
48 Tests
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PCR for diagnosis
This Cardio Trombophilia Panel Real Time PCR kit for detection of 8 mutations: F2 20210 G>A, F5 1691 G>A (Arg506Gln), F710976 G>A (Arg353Gln), F13 G>T (Val34Leu), FGB -455 G>A, ITGA2 807 C>T (Phe224Phe), ITGB3 1565 T>C(Leu33Pro), SERPINE1(PAI1) -675 5G>4G is used as PCR kit for molecular diagnostics with elecrtophoresis, qPCR or real-time PCR of 48 Tests per screening.
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ISO CE marked fro IVD
This molecular diagnostic PCR kit is CE approved and complies with the Directive 98/79/EC for IVD, in vitro PCR Diagnostics. The PCR kit is ISO 9001:2008 and ISO 13485:2012, CE marked with the in vitro diagnostic medical divices requirements Annex 2 of list B of the laboratory Directive 98/79/EC and can be used for diagnosis of viruses. The kit inculde all reagents for PCR or RT-PCR of viral DNA or RNA.
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Description
The detections of the targets with this kit is a type of test that can be performed on any target containing biological samples after clean up of interfering agents. The assay must be performed following the protocol.
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Group
PCR, polymerase chain reaction
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About
TAQ or Pfu or Pfx or other enzymes are used for polycmerase chain reaction and have different specificity. The mores specific the lower the yield.
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Properties
Thermocyclers can be callibrated for identical ramping curves to obtain a more accurate PCR.
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Gene target
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Gene symbol
SERPINE1, FGB, ITGA2-AS1, ITGA2, ITGB3
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Short name
Cardio Trombophilia Panel Real Time PCR kit for of 8 mutations: F2 20210 G>A, F5 1691 G>A (Arg506Gln), F710976 G>A (Arg353Gln), F13 G>T (Val34Leu), FGB -455 G>A, ITGA2 807 C>T (Phe224Phe), ITGB3 1565 T>C(Leu33Pro), SERPINE1(PAI1) -675 5G>4G
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Technique
detection, PCR, The polymerase chain reaction (PCR) amplifies the DNA in your sample. For real time PCR the cycle threshold Ct values willneed to be set before the experiment. Than the RT-PCR starts from RNA and real time PCR quantitates the cDNA so the RNA in the sample on given time of the experiment.
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Alternative name
Cardio Trombophilia Panel Quantitative real-time PCR test kit reagent to measure quantification on 8 mutations: coagulation factor II (thrombin) 20210 G>A, coagulation factor V (proaccelerin, labile factor) 1691 G>A (Arg506Gln), F710976 G>A (Arg353Gln), F13 G>T (Val34Leu), fibrinogen beta chain -455 G>A, integrin, alpha 2 (CD49B, alpha 2 subunit on VLA-2 receptor) 807 C>T (Phe224Phe), integrin, b 3 (platelet glycoprotein IIIa, antigen CD61) 1565 T>C(Leu33Pro), serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor classification 1), member 1(PAI1) -675 5G>4G
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Alternative technique
kits, dna-amplification
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Alternative to gene target
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832
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Tissue
panel
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Gene info
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Identity
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Gene
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Long gene name
serpin family E member 1
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Synonyms gene
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Synonyms gene name
- serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Serpin peptidase inhibitors
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene name
fibrinogen beta chain
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Synonyms gene name
- fibrinogen, B beta polypeptide
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Locus
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Discovery year
2001-06-22
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Entrez gene record
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RefSeq identity
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Classification
- Fibrinogen C domain containing
- Receptor ligands
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene name
ITGA2 antisense RNA 1
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Locus
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Discovery year
2021-04-12
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Classification
Gene info
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Identity
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Gene
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Long gene name
integrin subunit alpha 2
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Synonyms gene
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Synonyms gene name
- integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
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Synonyms
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Synonyms name
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Locus
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Discovery year
1991-08-06
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Entrez gene record
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RefSeq identity
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Classification
- Integrin alpha subunits
- CD molecules
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene name
integrin subunit beta 3
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Synonyms gene
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Synonyms gene name
- integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
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Synonyms
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Synonyms name
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Locus
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Discovery year
1988-06-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- Integrin beta subunits
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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Concept
Scope note:
Recording of pertinent information concerning patient's illness or illnesses.
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Tree numbers
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Qualifiers
classification, economics, legislation & jurisprudence, standards, statistics & numerical data
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