WTAP Polyclonal Antibody
-
Catalog numberCAC07914
-
PricePlease ask
-
Size100 μg
-
-
Other namePre-mRNA-splicing regulator WTAP,Female-lethal(2)D homolog,hFL(2)D,WT1-associated protein,Wilms tumor 1-associating protein,WTAP,KIAA0105
-
ImmunogenRecombinant Human Pre-mRNA-splicing regulator WTAP protein (1-151AA)
-
Verified reactivityHuman, Mouse, Rat
-
Verified applicationsELISA,WB,IHC,IF. Recommended dilution:WB:1:500-1:5000,IHC:1:20-1:200,IF:1:50-1:200
-
Raised inRabbit
-
ClonalityPolyclonal
-
Protein numberQ15007
-
Gene numberPlease refer to GenBank
-
NCBI numberPlease refer to NCBI
-
PurityProtein G purified, >95%
-
Storage recommendationAliquot and store at -20°C. Minimize freezing and thawing.
-
Use before1 year
-
Shipping requirementsBlue ice
-
Estimated production time3-7 business days
-
Supplementary informationRegulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing, processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle (PubMed:24316715, PubMed:24407421, PubMed:24981863). Acts as a mRNA splicing regulator (PubMed:12444081). Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability (PubMed:17088532). Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes (PubMed:17095724).
-
NotesFor research use only. Not for diagnostic procedures.
-
PropertiesIf you buy Antibodies supplied by bioma they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
GroupPolyclonals and antibodies
-
AboutPolyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
-
French translationanticorps
-
Gene target
-
Gene symbolWTAP
-
Short nameWTAP Polyclonal Antibody
-
TechniquePolyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
-
LabelUnconjugated
-
Alternative nameWTAP polyclonal (antibody to-)
-
Alternative techniquepolyclonals, antibodies
-
Gene info
-
Identity
-
Gene
-
Long gene nameWT1 associated protein
-
Synonyms gene name
- Wilms tumor 1 associated protein
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2003-05-19
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- m6A methyltransferase complex
- WTAP complex
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data