Acetyl and Histone H3(Ac-K10/p-Ser11) Antibody
-
Catalog number
bs-3748R
-
Price
Please ask
-
Size
0.1ml
-
-
Long name
Acetyl and Histone H3(Ac-K10/p-Ser11) Antibody
-
Also known as
Acetyl and Histone H3(Ac-K10/p-Ser11) Antibody
-
Category
Primary Antibodies
-
Conjugation
Unconjugated
-
Target Antigen
Acetyl and Histone H3(Ac-K10/p-Ser11)
-
Specificity
This is a highly specific antibody against Acetyl and Histone H3(Ac-K10/p-Ser11).
-
Modification s
Acetylation
-
Modification site s
Ac-K10/p-Ser11
-
Clonality
Polyclonal antibody
-
Clone number
Polyclonal antibody
-
Concentration
1ug per 1ul
-
Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Acetyl and Histone H3 (Ac-Lys10/p-Ser11)
-
Tested Applications
WB, IHC-P, IF(IHC-P)
-
Recommended dilutions
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
-
Cross reactivity
Human, Mouse, Rat
-
Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the target antigen
Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. The N-terminal tail of core histones undergoes different posttranslational modifications including acetylation, phosphorylation and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.
-
Purification method
This antibody was purified via Protein A.
-
Storage conditions
Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
-
Synonym names
H3 histone family member E pseudogene; H3F3; HIST3H3; Histone H3 3 pseudogene.
-
Description
N terminal acetylation or CH3CO as epigenetic regulation of Anti-Acetyl and Histone H3(Ac-K10/p-Ser11) by NATs.
-
Properties
If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translation
anticorps
-
Gene target
-
Gene symbol
KRT10
-
Short name
Anti-Acetyl and Histone H3(Ac-K10/p-Ser11)
-
Technique
Antibody, antibodies against human proteins, antibodies for
-
Host
Rabbit (Oryctolagus cuniculus)
-
Isotype
Immunoglobulin G (IgG)
-
Alternative name
Acetyl and Histone H3(Ac-K10/p-Ser11) Antibody
-
Alternative technique
antibodies
-
Gene info
-
Identity
-
Gene
-
Long gene name
keratin 10
-
Synonyms gene
-
Synonyms gene name
- keratosis palmaris et plantaris
- keratin 10, type I
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year
1988-08-12
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
-
VEGA ID
MeSH Data
-
Name
-
Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Similar products