Pleiotrophin Recombinant Protein

• Catalog number
  40-503
• Price
  Please ask
• Size
  0.005 mg, 0.02 mg

• About recombinant protein
  Pleiotrophin and Midkine are structurally related heparin-binding neurotrophic factors, whose expression is developmentally regulated. The expression pattern of these neurotrophic factors suggests function in neurogenesis, cell migration, secondary organogenetic induction, and mesoderm epithelial interaction. The expression of PTN increases during the process of brain embryogenesis and reaches maximum levels at time of birth. The physiological roles of PTN and Midkine are largely unknown, but these neurotrophins have been implicated in the pathogenesis of neuroblastomas. Recombinant human Pleiotrophin is a 15.4 kDa protein containing 136 amino acid residues and five intra-molecular disulfide bonds.
• Other name of the recombinant
  HARP, HBNF, HBGF8, NEGF1, HBNF1, Pleiotrophin, Heparin-binding brain mitogen, PTN
• Recombinant in
  E. coli
• SEQUENCE
  GKKEKPEKKV KKSDCGEWQW SVCVPTSGDC GLGTREGTRT GAECKQTMKT QRCKIPCNWK KQFGAECKYQ FQAWGECDLN TALKTRTGSL KRALHNAECQ KTVTISKPCG KLTKPKPQAE SKKKKKEGKK QEKMLD
• Keep at
  The lyophilized Pleiotrophin recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted Pleiotrophin is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing Pleiotrophin recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
• Rec PROTEIN GI
  4506281
• Accession nr
  NP_002816.1
• Pureity
  Greater than 98% by SDS-PAGE gel and HPLC analyses.Endotoxin level is less than 0.1 ng per μg (1EU/μg).
• About
  This product is for research use only.
• Protein s origin
  Human
• Vial
  Lyophilized
• NCBI ID
  5764
• Gene name
  pleiotrophin
• Source
  Homo sapiens
• Uniprot
  P21246
• Pictures of recombinant
• Rec pdf
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Pleiotrophin   Protein  
• Gene symbol
  PTN
• Short name
  Pleiotrophin Recombinant Protein
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. proscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Alternative name
  Pleiotrophin Rec. Protein
• Alternative technique
  rec

Gene info

• Identity
  HGNC:9630
• Gene
  PTN
• Long gene name
  pleiotrophin
• Synonyms gene
  • NEGF1
• Synonyms gene name
  • neurite growth-promoting factor 1
• Synonyms
  • HBNF
  • HBGF8
• Synonyms name
  • heparin binding growth factor 8
• GenBank acession
  • M57399
• Locus
  7q33
• Discovery year
  1993-06-22
• Entrez gene record
  5764
• Pubmed identfication
  • 1457401
  • 1768439
• RefSeq identity
  • NM_002825
• Classification
  • Receptor ligands
• VEGA ID
  OTTHUMG00000155709

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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