KLRC2, human recombinant

  • Catalog number
    7353-50
  • Price
    Please ask
  • Size
    50 ug
  • Synonyms
    NKG2-C type II integral membrane protein, CD159c, NKG2-C, NKG2C
  • Alternative_names
    NKG2-C type II integral membrane protein, CD159c, NKG2-C, NKG2C
  • Description
    Plays a role as a receptor for the recognition of MHC class I HLA-E molecules
  • Recombinant
    Yes
  • Source
    E. coli
  • Purity by SDS PAGE
    ≥85%
  • Assay
    SDS-PAGE
  • Molecular Weight
    18.4 kDa (162 aa, 94-231 aa + His Tag), confirmed by MALDI-TOF.
  • Storage Temp
    -80°C
  • Shipping
    Dry Ice
  • Shelf Life
    12 months
  • Concentration
    0.5 mg/ml
  • Appearance
    Liquid
  • Physical form description
    0.5 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea and 10% glycerol.
  • Background Information
    NKG2-C type II integral membrane protein, also known as KLRC2, plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. KLRC2 alternative splice variants have been described but their full-length nature has not been determined. Recombinant human KLRC2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
  • Amino acid sequence
    MGSSHHHHHH SSGLVPRGSH MGSM IPFLEQ NNFSPNTRTQ KARHCGHCPE EWITYSNSCY YIGKERRTWE ESLLACTSKN SSLLSIDNEE EMKFLASILP SSWIGVFRNS SHHPWVTING LAFKHKIKDS DNAELNCAVL QVNRLKSAQC GSSMIYHCKH KL
  • Handling
    Centrifuge the vial prior to opening.
  • Usage
    For Research Use Only! Not to be used in humans
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Additional source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
    KLRC2  
  • Gene symbol
    KLRC2
  • Short name
    KLRC2, recombinant
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Species
    Human, Humans
  • Alternative name
    NKG2-C classification II integral membrane protein, H. sapiens Rec.
  • Alternative technique
    rec
  • Alternative to gene target
    NKG2-C type II integral membrane protein, KLRC2 and IDBG-545486 and ENSG00000255641 and, carbohydrate binding, multiple
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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