LAG-3 (Lymphocyte Activation Gene-3, FDC Protein, CD223) (FITC) Antibody

• Catalog number
  GEN609777
• Price
  Please ask
• Size
  100ug

• Also known as
  LAG-3
• Other names
  LAG-3 protein; N/A
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  N/A
• Gene name synonims
  N/A
• Other gene names
  N/A
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG1
• Clone
  6D65
• Host organism
  Mouse (Mus musculus)
• Source organism
  Human (Homo sapiens)
• Species reactivity
  Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Recognizes the 30aa extra-loop of the first N-terminal D1 domain of human LAG-3.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Affinity Purified by Protein A sepharose chromatography. (>95% by SDS-PAGE).
• Form Appearance
  Supplied as a liquid in PBS, 0.02% sodium azide. Labeled with fluorescein isothiocyanate (FITC).
• Concentration
  1 miligram per 1 mililiter
• Storage and shipping
  Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. FITC conjugates are sensitive to light.
• Tested applications
  Flow Cytometry (FC/FACS)
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This MBS Monoclonals Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. MBS Monoclonals FITC is highly sensitive to pH extremes.
• Conjugation
  Anti-FITC Antibody
• Description
  cDNA genes are a locus (or region) of DNA for functional transcript RNA or protein. An ELISA is used to detect the expressed protein in biological fluids, serum, saliva.
• French translation
  anticorps

• Gene target
  LAG-3   Lymphocyte   Activation   Gene-3   FDC   Protein   CD223  
• Gene symbol
  LAG3, FDCSP, GNLY, MIR1302-3, MIR509-3, MIR7-3, PIRC13
• Short name
  LAG-3 (Lymphocyte Activation -3, FDC Protein, CD223) (FITC) Antibody
• Technique
  activation, Antibody, FITC, antibodies against human proteins, antibodies for, Fluorescein
• Label
  FITC
• Alternative name
  Anti-LAG-3 (Lymphocyte Activation Gene-3, FDC Protein, CD223) (FITC)
• Alternative technique
  antibodies, fluorescine
• Tissue
  lymphocyte

Gene info

• Identity
  HGNC:6476
• Gene
  LAG3
• Long gene name
  lymphocyte activating 3
• Synonyms gene name
  • lymphocyte-activation gene 3
• Synonyms
  • CD223
• Locus
  12p13.31
• Discovery year
  1991-06-03
• Entrez gene record
  3902
• RefSeq identity
  • NM_002286
• Classification
  • Immunoglobulin like domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000169197

Gene info

• Identity
  HGNC:19215
• Gene
  FDCSP
• Long gene name
  follicular dendritic cell secreted protein
• Synonyms gene
  • C4orf7
• Synonyms gene name
  • chromosome 4 open reading frame 7
• Synonyms
  • FDC-SP
• GenBank acession
  • AF435080
• Locus
  4q13.3
• Discovery year
  2002-09-17
• Entrez gene record
  260436
• Pubmed identfication
  • 12193705
  • 17548624
  • 20811673
• RefSeq identity
  • NM_152997
• VEGA ID
  OTTHUMG00000129393

Gene info

• Identity
  HGNC:4414
• Gene
  GNLY
• Long gene name
  granulysin
• Synonyms gene
  • LAG2
• Synonyms
  • NKG5
  • LAG-2
  • D2S69E
  • TLA519
• Synonyms name
  • T-lymphocyte activation gene 519
• GenBank acession
  • X54101
• Locus
  2p11.2
• Discovery year
  1999-11-22
• Entrez gene record
  10578
• Pubmed identfication
  • 2212946
  • 2434598
• RefSeq identity
  • NM_006433
• VEGA ID
  OTTHUMG00000130179

Gene info

• Identity
  HGNC:35295
• Gene
  MIR1302-3
• Long gene name
  microRNA 1302-3
• Synonyms gene
  • MIRN1302-3
• Synonyms
  • hsa-mir-1302-3
• Locus
  2q14.1
• Discovery year
  2008-11-03
• Entrez gene record
  100302128
• RefSeq identity
  • NR_031632
• Classification
  • MicroRNA MIR1302 family

Gene info

• Identity
  HGNC:33675
• Gene
  MIR509-3
• Long gene name
  microRNA 509-3
• Synonyms gene
  • MIRN509-3
• Synonyms
  • hsa-mir-509-3
• Locus
  Xq27.3
• Discovery year
  2007-10-24
• Entrez gene record
  100126337
• RefSeq identity
  • NR_030629
• Classification
  • MicroRNA MIR506 family

Gene info

• Identity
  HGNC:31640
• Gene
  MIR7-3
• Long gene name
  microRNA 7-3
• Synonyms gene
  • MIRN7-3
• Synonyms
  • hsa-mir-7-3
• Locus
  19p13.3
• Discovery year
  2004-04-23
• Entrez gene record
  407045
• RefSeq identity
  • NR_029607
• Classification
  • MicroRNA MIR7 family

Gene info

• Identity
  HGNC:37517
• Gene
  PIRC13
• Long gene name
  piwi-interacting RNA cluster 13
• Locus
  3
• Discovery year
  2009-11-05
• Entrez gene record
  100313925
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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