BMP-6, human recombinant
-
Catalog number4911-10MG
-
PricePlease ask
-
Size10 mg
-
-
SynonymsVGR, VGR1, BMP-6
-
Alternative_namesVGR, VGR1, BMP-6, VG-1-related protein
-
DescriptionInduces all osteogenic markers in mesenchymal stem cells.
-
RecombinantYes
-
SourceE. coli
-
Purity by SDS PAGE≥98%
-
AssaySDS-PAGE
-
Purity≥98%
-
Biological activityBioVision’s recombinant human BMP-6 is biologically active. The ED₅₀ as determined by dose-dependent induction of alkaline phosphatase activity with C2C12 cells is in the range of 2-12 µg/ml.
-
Results2-12 µg/ml
-
Molecular Weightmonomer (15 kDa), dimer (30 kDa)
-
Storage Temp-20°C
-
ShippingGel pack
-
Shelf Life12 months
-
AppearanceLyophilized protein
-
Physical form descriptionSterile filtered and lyophilized with no additives
-
Reconstitution InstructionsReconstitute to a concentration of 0.1-1.0 mg/ml in sterile 20 mM acetic acid. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
-
Background InformationBMPs (bone morphogenetic proteins) belong to the TGF-β superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. Recombinant human BMP-6 produced from E. coli contains a mixture of monomer (15 kDa), dimer (30 kDa), and multimers. The dimer is an active polypeptide chain containing 2X142 amino acid residues.
-
HandlingCentrifuge the vial prior to opening.
-
UsageFor Research Use Only! Not to be used in humans
-
PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
-
Additional sourceRecombinants or rec. proteins
-
Grouprecombinants
-
Gene target
-
Gene symbolBMP6, GDF11, GDF10, BMP1, GDF2, MIR1302-6, PIRC28, PIRC24, PIRC26, PIRC27
-
Short nameBMP-6, recombinant
-
TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
-
SpeciesHuman, Humans
-
Alternative nameBMP-6, H. sapiens Rec.
-
Alternative techniquerec
-
Gene info
-
Identity
-
Gene
-
Long gene namebone morphogenetic protein 6
-
Synonyms gene
-
Synonyms gene name
- vegetal related growth factor (TGFB-related)
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1991-06-05
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Bone morphogenetic proteins
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namegrowth differentiation factor 11
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1999-12-02
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Transforming growth factor beta superfamily
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namegrowth differentiation factor 10
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1997-09-12
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Transforming growth factor beta superfamily
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namebone morphogenetic protein 1
-
Synonyms gene
-
Synonyms gene name
- procollagen C-endopeptidase
-
Synonyms
-
Synonyms name
-
Locus
-
Discovery year1990-06-11
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Bone morphogenetic proteins
- Astacins
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namegrowth differentiation factor 2
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1997-09-12
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Transforming growth factor beta superfamily
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namemicroRNA 1302-6
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year2008-11-03
-
Entrez gene record
-
RefSeq identity
-
Classification
- MicroRNA MIR1302 family
Gene info
-
Identity
-
Gene
-
Long gene namepiwi-interacting RNA cluster 28
-
Locus
-
Discovery year2009-11-05
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Piwi-interacting RNA clusters
Gene info
-
Identity
-
Gene
-
Long gene namepiwi-interacting RNA cluster 24
-
Locus
-
Discovery year2009-11-05
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Piwi-interacting RNA clusters
Gene info
-
Identity
-
Gene
-
Long gene namepiwi-interacting RNA cluster 26
-
Locus
-
Discovery year2009-11-05
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Piwi-interacting RNA clusters
Gene info
-
Identity
-
Gene
-
Long gene namepiwi-interacting RNA cluster 27
-
Locus
-
Discovery year2009-11-05
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Piwi-interacting RNA clusters
MeSH Data
-
Name
-
ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
-
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
