anti-SIRT7 Antibody

• Catalog number
  49-312
• Price
  Please ask
• Size
  0.05 mg

• Gene info
  SIRT7 is a human member of a family of proteins called Sirtuins (Sir2-like proteins) and are present in prokaryotes and eukaryotes. All Sir2-like proteins have a sirtuin core domain, which contains a series of sequence motifs conserved in organisms ranging from bacteria to humans. Bacterial, yeast and mammalian sirtuins are able to metabolize NAD and possibly at as mono-ADP-ribosyltransferases. The enzymatic function of sirtuins is not yet completely understood but recent reports of histone-activated Sir2-mediated NAD metabolism and NAD-activated Sir2-mediated histone deacetylation suggest a possible coupled reciprocal activation mechanism involving interactions of Sir2 with NAD and the N epsilon-acetyl-lysine groups of acetylated histones.
• Gene names
  SIRT7, SIR2L7, Sirtuin type 7, SIR2-like protein 7, Sir2-related protein type 7, Sirtuin 7
• Antibodie s label
  unlabelled serum
• Purity
  Protein G Column
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  SIRT7 antibody was made against amino acids 35 - 51 of SIRT7 (Human).
• Immuno application
  Western Blot, immuno-histo-chemistry
• Antibody advice
  SIRT7 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, and immunohistochemistry starting at 2.5 ug/mL.
• Suspention pH azide
  PBS, 0.2% gelatin, 0.05% sodium azide.
• Keep at
  SIRT7 antibody should be stored long term (months) at -20 grades C and short term (weeks) at 4 grades C. As with all antibodies avoid freeze/thaw cycles.
• Works with
  Human
• Omim nr
  38258650
• Ncbi nr
  Q9NRC8
• Vial with antibody
  in solution
• NCBI GENE nr
  51547
• GENE symbol
  SIRT7
• Antigene name
  sirtuin 7
• Source
  Homo sapiens
• Protein nr
  Q9NRC8
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SIRT7  
• Gene symbol
  SIRT7
• Short name
  anti-SIRT7 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toSIRT7 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:14935
• Gene
  SIRT7
• Long gene name
  sirtuin 7
• Synonyms gene name
  • sirtuin (silent mating type information regulation 2, S.cerevisiae, homolog) 7
  • sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae)
• GenBank acession
  • AF233395
• Locus
  17q25.3
• Discovery year
  2001-03-20
• Entrez gene record
  51547
• Pubmed identfication
  • 10873683
  • 16618798
• RefSeq identity
  • NM_016538
• Classification
  • Sirtuins
• VEGA ID
  OTTHUMG00000177957

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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