Recombinant Programmed Cell Death Protein 1 Ligand 1 (PDCD1LG1)

• Catalog number
  RPA788Ra01
• Price
  Please ask
• Size
  470

• Source
  Prokaryotic expression
• Predicted Molecular Mass KD
  53.7kDa
• Accurate Molecular Mass KD
  64kDa
• Organism species
  Rattus norvegicus (Rat)
• Item Name
  Programmed Cell Death Protein 1 Ligand 1
• Alternative Names
  CD274; PDL1; B7-H; B7H1; PD-L1; PDCD1L1; PDCD1-LG1; Programed Death Ligand 1
• Research Area
  Signal transduction;Tumor immunity;Infection immunity;Immune molecule;Autoimmunity;
• Buffer Formulation
  100mMNaHCO3, 500mMNaCl, pH8.3, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Traits
  Freeze-dried powder
• Isoelectric Point
  8.2
• Purity
  ≥ 90%
• Protein length
  Ser34~Val241
• Tag
  two N-terminal Tags, His-tag and T7-tag
• Expression System
  Prokaryotic expression
• Application
  Positive Control; Immunogen; SDS-PAGE; WB.
• Manual link
• Description
  For cells, cell lines and tissues in culture till half confluency. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Programmed   Death   Protein   Ligand   PDCD1LG1  
• Gene symbol
  CD274
• Short name
  Recombinant Programmed Death Protein 1 Ligand 1 (PDCD1LG1)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Cloud Clone Corp advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  E.coli
• Species
  Rattus norvegicus (Rat)
• Alternative name
  Rec. Programmed cellular Death Protein 1 Ligand 1 (PDCD1LG1)
• Alternative technique
  rec
• Tissue
  cell

Gene info

• Identity
  HGNC:17635
• Gene
  CD274
• Long gene name
  CD274 molecule
• Synonyms gene
  • PDCD1LG1
• Synonyms gene name
  • programmed cell death 1 ligand 1
  • CD274 antigen
• Synonyms
  • B7-H
  • B7H1
  • PD-L1
  • PDL1
  • B7-H1
• Synonyms name
  • B7 homolog 1
• GenBank acession
  • AF177937
• Locus
  9p24.1
• Discovery year
  2003-11-13
• Entrez gene record
  29126
• Pubmed identfication
  • 11015443
  • 10581077
• RefSeq identity
  • NM_014143
• Classification
  • Receptor ligands
  • C2-set domain containing
  • V-set domain containing
  • B7 family
  • CD molecules
• VEGA ID
  OTTHUMG00000019503

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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