CBS Antibody (NT)

• Catalog number
  6729-100
• Price
  Please ask
• Size
  100 μl

• Antibody Target
  CBS
• Target Alternative Name
  CBS; Cystathionine beta-synthase; Beta-thionase; Serine sulfhydrase
• Antibody Type
  Polyclonal
• Species Reactivities
  Human and mouse
• Immunogen Sequence
  This CBS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-133 amino acids from the N-terminal region of human CBS.
• Accession
  P35520
• Gene Id
  875
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  100 µl of antibody in PBS with 0.09% (W/V) sodium azide
• Purification
  This antibody is purified through a protein A column, followed by peptide affinity purification.
• Application
  Western blot, IHC, FACS, IF
• Positive Control
  Western blot: Raji, Rat brain and cerebellum tissue lysate, IHC: human hepatocarcinoma, FACS: Ramos cells, IF: 293 cells
• Application And Usages
  Western blot: ~1:1000, IHC: ~1:50–1:100, IF: ~1:10–1:50, FACS: ~1:10-1:50.
• Description
  Strongly expressed in human liver and pancreas, with weaker expression in heart and brain, the cytoplasmic protein cystathionine b-synthase (CBS) operates in the first step of homocysteine transulfuration. CBS, which belongs to the cysteine synthase/cystathionine b-synthase family of proteins, catalyzes the formation of cystathionine from the thrombogenic amino acid homocysteine using pyridoxal phosphate cofactor. Allosteric activation by adenosyl-methionine regulates CBS activity. Deficiencies in CBS are associated with homocystinuria, a recessively inherited error in sulfur amino acid metabolism that affects many organs and tissues. Symptoms of homocytinuria include arteriosclerosis, thrombosis, dislocated optic lenses, mental retardation and skeletal abnormalities.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Verified
• Immunofluorescence Verified
  Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CBS  
• Gene symbol
  CBS, MSRB2
• Short name
  CBS Antibody (NT)
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  CBS (antibody to-) (NT)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:1550
• Gene
  CBS
• Long gene name
  cystathionine beta-synthase
• Synonyms gene name
  • cystathionine-beta-synthase
• Synonyms
  • HIP4
• GenBank acession
  • L14577
• Locus
  21q22.3
• Discovery year
  2001-06-22
• Entrez gene record
  875
• Pubmed identfication
  • 9790750
• RefSeq identity
  • NM_000071
• VEGA ID
  OTTHUMG00000086834
• Locus Specific Databases
  • Cystathionine beta-synthase database
  • LRG_777

Gene info

• Identity
  HGNC:17061
• Gene
  MSRB2
• Long gene name
  methionine sulfoxide reductase B2
• Synonyms gene
  • MSRB
• Synonyms gene name
  • methionine sulfoxide reductase B
• Synonyms
  • PILB
  • CGI-131
  • CBS1
  • CBS-1
• GenBank acession
  • AF122004
• Locus
  10p12.2
• Discovery year
  2004-02-03
• Entrez gene record
  22921
• Pubmed identfication
  • 8749308
  • 10375640
• RefSeq identity
  • NM_012228
• VEGA ID
  OTTHUMG00000017812

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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