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MMP 13 Collagenase 3 catalytic domain Recombinant Protein

MMP 13 Collagenase 3 catalytic domain Recombinant Protein is available 2 times from Biotez labs

30 100 812 | MMP 13 (Collagenase 3) catalytic domain (Recombinant Protein) size: 10 µg/ 50µl | 374.11 USD

Catalog number 30 100 812
Supplier biotez
Price 374.11 USD
Size 10 µg/ 50µl
1. Gene info
Identity7172
GeneMMP24
Synonyms gene name
  • matrix metalloproteinase 24 (membrane-inserted)
  • matrix metallopeptidase 24 (membrane-inserted)
Synonyms
GenBank acession
Discovery year1999-08-06
Pubmed identfication
RefSeq identity
Havana BLAST/BLATOTTHUMG00000032330
MeSH Data
Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500

30 100 813 | MMP 13 (Collagenase 3) catalytic domain (Recombinant Protein) size: 200 µg/ 1 ml | 5,474.00 USD

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Abbreviation MMP13 (partial)
Expression system E.coli
Other names Matrix Metalloproteinase 13 (Collagenase 3)
Protein subtype EC 3.4.24.35
Protein description MMP13 plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CTGF. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion
Product Subtype protein fragment
Molecular weight 19.5 kDa
Gene number 4322
Package form liquid
Storage condition Store at -70°C
Tested applications Degradation of extracellular Matrix; Screening and evaluation of MMP inhibitors; Antigen standard
Full name matrix metallopeptidase 13 partial
Shipping conditions dry ice
Purification Mentioned in the data sheet
Research area interests Diseases associated with MMP13 include Spondyloepimetaphyseal Dysplasia, Missouri Type and Metaphyseal Dysplasia, Spahr Type. Among its related pathways are Integrin Pathway and Development_Glucocorticoid receptor signaling.
Other desciption Recombinant human procollagenase-3 catalytic domain is expressed in E. coli.
Peptide sequence Y N V F P R T L K W S K M N L T Y R I V N Y T P D M T H S E V E K A F K K A F K V W S D V T P L N F T R L H D G I A D I M I S F G I K E H G D F Y P F D G P S G L L A H A F P P G P N Y G G D A H F D D D E T W T S S S K G Y N L F L V A A H E F G H S L G L D H S K D P G A L M F P I Y T Y T G K S H F M L P D D D V Q G I Q S L Y G P G D E D P N
Technical datasheet Contact us to receive the datasheet
Active form? Yes
Contents 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 5 mM CaCl2
Available target modification No
Protein purity >95%
Protein family Matrix Metalloproteinases, matrixins
Tag untagged
UniProt number P45452
PubMed citations See the data sheet
Warnings For Research Use only.
Protein type Recombinant
Source Recombinants or rec. proteins
Group recombinants
Short name MMP 13 (Collagenase 3) catalytic domain (Recombinant Protein)
Technique Recombinant
Alternative name MMP 13 (Collagenase 3) catalytic domain (recombinant Protein)
Alternative technique rec
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