LYK5 Antibody

• Catalog number
  bs-3949R
• Price
  Please ask
• Size
  0.1ml

• Long name
  LYK5 Primary Polyclonal Antibody
• Also known as
  LYK5 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  LYK5
• Specificity
  This is a highly specific antibody against LYK5.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LYK5
• Gene ID number
  92335
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Members of the STE-20 like kinase family are known to stimulate MAPK pathways by directly activating MAPKKK. LYK5 is a novel pseudokinase member of this family consisting of a STE-20 like kinase domain but lacks several residues that are required for its catalytic activity. It specifically binds LKB1 and plays a key role in regulating the tumor suppressor activities of LKB1. It functions as an upstream activator of LKB1 and also directs the sub-cellular localization of LKB1 by anchoring it in the cytoplasm. LYK5-LKB1 interaction results in phosphorylation of LYK5 and enhanced autophosphorylation of LKB1.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Serologically defined breast cancer antigen NY BR 96; STRAD alpha; Protein kinase LYK5; STE20 related adapter protein; STRAD; STRAA_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  LYK5  
• Gene symbol
  STRADA
• Short name
  Anti-LYK5
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  LYK5 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:30172
• Gene
  STRADA
• Long gene name
  STE20 related adaptor alpha
• Synonyms gene name
  • STE20-related kinase adaptor alpha
• Synonyms
  • NY-BR-96
  • LYK5
  • Stlk
  • STRAD
• Synonyms name
  • STE20-like pseudokinase
• GenBank acession
  • AF308302
• Locus
  17q23.3
• Discovery year
  2008-09-15
• Entrez gene record
  92335
• Pubmed identfication
  • 12805220
  • 17921699
• VEGA ID
  OTTHUMG00000178908

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products