Tandutinib

• Catalog number
  2024-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  MLN518; CT53518
• Description
  Cell-permeable. A potent inhibitor of Fms-like tyrosine kinase 3 (FLT3) kinase, PDGFRβ and c-Kit (IC50’s 95-122 ng/ml).   It inhibits FLT3 phosphorylation, downstream signaling and tumor growth in vitro and in animal models.
• CAS Number
  387867-13-2
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₃₁H₄₂N₆O₄
• Molecular Weight
  562.7
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (~ 25 mg/ml) or EtOH (~ 25 mg/ml)
• Handling
  Protect from air and moisture
• Tag Line
  A potent inhibitor of FLT kinase, PDGFRβ and c-Kit
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24 months
• MDL Number
  MFCD09954147
• PubChem CID
  3038522
• PubChem CID Link
• SMILES
  CC(C)OC1=CC=C(C=C1)NC(=O)N2CCN(CC2)C3=NC=NC4=CC(=C(C=C43)OC)OCCCN5CCCCC5
• InChi
  InChI=1S/C31H42N6O4/c1-23(2)41-25-10-8-24(9-11-25)34-31(38)37-17-15-36 (16-18-37)30-26-20-28(39-3)29(21-27(26)32-22-33-30)40-19-7-14-35-12-5-4- 6-13-35/h8-11,20-23H,4-7,12-19H2,1-3H3,(H,34,38)
• InChi Key
  UXXQOJXBIDBUAC-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Tandutinib  
• Short name
  Tandutinib
• Alternative name
  Tandutinib

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