RAT ANTI MOUSE DECTIN-1:Biotin Antibody

  • Catalog number
    GEN215790
  • Price
    Please ask
  • Size
    100ug
  • Also known as
    DECTIN-1
  • Other names
    C-type lectin domain family 7 member A; C-type lectin domain family 7 member A; C-type lectin domain family 7 member A; dectin-1; beta-glucan receptor; DC-associated C-type lectin 1; C-type lectin superfamily member 12; dendritic cell-associated C-type lectin 1; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12; C-type lectin domain family 7, member a; Beta-glucan receptor; C-type lectin superfamily member 12; Dendritic cell-associated C-type lectin 1
  • Category
    Antibodies
  • Subcategory
    Mnoclonal antibodies
  • Gene name
    Clec7a; Clec7a; BGR; beta-GR; Clecsf12; Bgr; Clecsf12; Dectin1; DC-associated C-type lectin 1; Dectin-1
  • Gene name synonims
    Clec7a; Clec7a; BGR; beta-GR; Clecsf12; Bgr; Clecsf12; Dectin1; DC-associated C-type lectin 1; Dectin-1
  • Other gene names
    Clec7a; Clec7a; BGR; beta-GR; Clecsf12; Bgr; Clecsf12; Dectin1; DC-associated C-type lectin 1; Dectin-1
  • Clonality
    Monoclonal
  • Immunoglobulin isotype
    IgG2b
  • Clone
    2A11
  • Host organism
    Rat (Rattus norvegicus)
  • Species reactivity
    Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
  • Specificity and cross reactivity
    DECTIN-1 This item recognises murine beta-glucan receptor, also known as Dectin-1._x000D_Dectin-1 is predominantly expressed by cells of the monocyte/macrophage and neutrophil lineages, but also at lower levels by dendritic cells and a subpopulation of T cells. _x000D__x000D_As a major leucocyte receptor for beta-glucan this molecule may have a key role in the immunomodulatory effects of beta-glucans and in the host response to fungal pathogens. _x000D__x000D_Recent work has shown that Dectin-1 may stimulate reactive oxygen production in macropahges via the protein tyrosine kinase known as Syk. _x000D__x000D_This antibody inhibits the binding of zymosan to macrophages via the beta-glucan receptor.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
  • Purification method
    N/A
  • Form Appearance
    Biotin (Purified IgG conjugated to Biotin - liquid)
  • Concentration
    IgG concentration 0.1 miligram per 1 mililiter
  • Storage and shipping
    Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term. the antibody should be stored undiluted. Storage in frost-free freezers is not recommended. the antibody is photosensitive and should be protected from light. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.
  • Tested applications
    Flow Cytometry (FACS)
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. This is against a protein of mus musculus directed antibody.
  • Properties
    If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
  • Conjugation
    Biotinylated
  • Test
    Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
  • Latin name
    Mus musculus, Rattus norvegicus
  • About
    Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
  • French translation
    anticorps
  • Gene target
  • Gene symbol
    CLEC7A, CLEC6A, CLEC4D, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR101-1, MIR1289-1
  • Short name
    ANTI MOUSE DECTIN-1: Antibody
  • Technique
    anti mouse, Antibody, Mouse, anti, antibody to, anti mouse antibodies, antibodies against human proteins, antibodies for, mouses
  • Host
    Rat
  • Label
    Biotin
  • Species
    Mouse, Mouses, Rats
  • Alternative name
    Anti-RAT ANTI MOUSE DECTIN-1:Biotin
  • Alternative technique
    antibodies, murine
Gene info
  • Identity
  • Gene
  • Long gene name
    C-type lectin domain containing 7A
  • Synonyms gene
  • Synonyms gene name
    • C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12
    • C-type lectin domain family 7, member A
    • C-type lectin domain family 7 member A
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2001-02-01
  • Entrez gene record
  • RefSeq identity
  • Classification
    • C-type lectin domain containing
    • CD molecules
    • Scavenger receptors
  • VEGA ID
  • Locus Specific Databases
Gene info
  • Identity
  • Gene
  • Long gene name
    C-type lectin domain containing 6A
  • Synonyms gene
  • Synonyms gene name
    • C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 10
    • C-type lectin domain family 6, member A
    • C-type lectin domain family 6 member A
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2004-11-18
  • Entrez gene record
  • RefSeq identity
  • Classification
    • C-type lectin domain containing
  • VEGA ID
Gene info
  • Identity
  • Gene
  • Long gene name
    C-type lectin domain family 4 member D
  • Synonyms gene
  • Synonyms gene name
    • C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 8
    • C-type lectin domain family 4, member D
  • Synonyms
  • Synonyms name
  • GenBank acession
  • Locus
  • Discovery year
    2004-10-20
  • Entrez gene record
  • RefSeq identity
  • Classification
    • C-type lectin domain containing
    • CD molecules
  • VEGA ID
Gene info
  • Identity
  • Gene
  • Long gene name
    immunoglobulin heavy variable (II)-1-1 (pseudogene)
  • Synonyms gene name
    • immunoglobulin heavy variable (II)-1-1
    • immunoglobulin heavy variable (II)-1-1 pseudogene
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2000-04-17
  • Entrez gene record
  • RefSeq identity
  • Classification
    • Immunoglobulin heavy locus at 14q32.33
  • VEGA ID
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    tRNA-undetermined (NNN) 8-1
  • Synonyms gene name
    • transfer RNA-undetermined (NNN) 8-1
  • GenBank acession
  • Locus
    1
  • Discovery year
    2014-06-20
  • Entrez gene record
  • Pubmed identfication
Gene info
  • Identity
  • Gene
  • Long gene name
    tRNA-undetermined (NNN) 7-1
  • Synonyms gene name
    • transfer RNA-undetermined (NNN) 7-1
  • GenBank acession
  • Locus
    1
  • Discovery year
    2014-06-20
  • Entrez gene record
  • Pubmed identfication
Gene info
  • Identity
  • Gene
  • Long gene name
    immunoglobulin kappa variable 1/OR2-1 (pseudogene)
  • Synonyms gene
  • Synonyms gene name
    • immunoglobulin kappa variable 1/OR-1
    • immunoglobulin kappa variable 1/OR-1 pseudogene
    • immunoglobulin kappa variable 1/OR-1 (pseudogene)
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2000-04-18
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • Immunoglobulin kappa (IGK) orphons
  • VEGA ID
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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