RAT ANTI MOUSE DECTIN-1:Biotin Antibody
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Catalog numberGEN215790
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PricePlease ask
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Size100ug
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Also known asDECTIN-1
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Other namesC-type lectin domain family 7 member A; C-type lectin domain family 7 member A; C-type lectin domain family 7 member A; dectin-1; beta-glucan receptor; DC-associated C-type lectin 1; C-type lectin superfamily member 12; dendritic cell-associated C-type lectin 1; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12; C-type lectin domain family 7, member a; Beta-glucan receptor; C-type lectin superfamily member 12; Dendritic cell-associated C-type lectin 1
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CategoryAntibodies
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SubcategoryMnoclonal antibodies
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Gene nameClec7a; Clec7a; BGR; beta-GR; Clecsf12; Bgr; Clecsf12; Dectin1; DC-associated C-type lectin 1; Dectin-1
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Gene name synonimsClec7a; Clec7a; BGR; beta-GR; Clecsf12; Bgr; Clecsf12; Dectin1; DC-associated C-type lectin 1; Dectin-1
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Other gene namesClec7a; Clec7a; BGR; beta-GR; Clecsf12; Bgr; Clecsf12; Dectin1; DC-associated C-type lectin 1; Dectin-1
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ClonalityMonoclonal
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Immunoglobulin isotypeIgG2b
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Clone2A11
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Host organismRat (Rattus norvegicus)
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Species reactivityMouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivityDECTIN-1 This item recognises murine beta-glucan receptor, also known as Dectin-1._x000D_Dectin-1 is predominantly expressed by cells of the monocyte/macrophage and neutrophil lineages, but also at lower levels by dendritic cells and a subpopulation of T cells. _x000D__x000D_As a major leucocyte receptor for beta-glucan this molecule may have a key role in the immunomodulatory effects of beta-glucans and in the host response to fungal pathogens. _x000D__x000D_Recent work has shown that Dectin-1 may stimulate reactive oxygen production in macropahges via the protein tyrosine kinase known as Syk. _x000D__x000D_This antibody inhibits the binding of zymosan to macrophages via the beta-glucan receptor.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification methodN/A
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Form AppearanceBiotin (Purified IgG conjugated to Biotin - liquid)
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ConcentrationIgG concentration 0.1 miligram per 1 mililiter
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Storage and shippingStore the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term. the antibody should be stored undiluted. Storage in frost-free freezers is not recommended. the antibody is photosensitive and should be protected from light. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.
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Tested applicationsFlow Cytometry (FACS)
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. This is against a protein of mus musculus directed antibody.
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PropertiesIf you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
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ConjugationBiotinylated
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TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus, Rattus norvegicus
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AboutRats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
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French translationanticorps
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Gene target
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Gene symbolCLEC7A, CLEC6A, CLEC4D, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR101-1, MIR1289-1
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Short nameANTI MOUSE DECTIN-1: Antibody
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Techniqueanti mouse, Antibody, Mouse, anti, antibody to, anti mouse antibodies, antibodies against human proteins, antibodies for, mouses
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HostRat
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LabelBiotin
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SpeciesMouse, Mouses, Rats
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Alternative nameAnti-RAT ANTI MOUSE DECTIN-1:Biotin
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Alternative techniqueantibodies, murine
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Gene info
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Identity
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Gene
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Long gene nameC-type lectin domain containing 7A
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Synonyms gene
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Synonyms gene name
- C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12
- C-type lectin domain family 7, member A
- C-type lectin domain family 7 member A
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-02-01
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Entrez gene record
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RefSeq identity
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Classification
- C-type lectin domain containing
- CD molecules
- Scavenger receptors
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameC-type lectin domain containing 6A
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Synonyms gene
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Synonyms gene name
- C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 10
- C-type lectin domain family 6, member A
- C-type lectin domain family 6 member A
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-11-18
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Entrez gene record
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RefSeq identity
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Classification
- C-type lectin domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameC-type lectin domain family 4 member D
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Synonyms gene
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Synonyms gene name
- C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 8
- C-type lectin domain family 4, member D
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-10-20
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Entrez gene record
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RefSeq identity
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Classification
- C-type lectin domain containing
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy variable (II)-1-1 (pseudogene)
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Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-17
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin heavy locus at 14q32.33
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1/206 family
Gene info
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Identity
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Gene
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Long gene nametRNA-undetermined (NNN) 8-1
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Synonyms gene name
- transfer RNA-undetermined (NNN) 8-1
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GenBank acession
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Locus
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Discovery year2014-06-20
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Entrez gene record
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Pubmed identfication
Gene info
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Identity
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Gene
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Long gene nametRNA-undetermined (NNN) 7-1
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Synonyms gene name
- transfer RNA-undetermined (NNN) 7-1
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GenBank acession
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Locus
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Discovery year2014-06-20
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Entrez gene record
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Pubmed identfication
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin kappa variable 1/OR2-1 (pseudogene)
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Synonyms gene
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Synonyms gene name
- immunoglobulin kappa variable 1/OR-1
- immunoglobulin kappa variable 1/OR-1 pseudogene
- immunoglobulin kappa variable 1/OR-1 (pseudogene)
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-18
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Entrez gene record
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Pubmed identfication
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Classification
- Immunoglobulin kappa (IGK) orphons
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 101-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR101 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1289-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2008-11-03
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1289 family
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data