Mouse anti SNAP25

• Catalog number
  X1598M
• Price
  Please ask
• Size
  100 μg

• Category
  Primary Antibodies
• Long description
  SNAP25 (Synaptosome-Associated Protein of 25 kDa) is a membrane bound, pre-synaptic nerve terminal protein that plays an essential role in synaptic vesicle fusion and exocytosis. It is involved in the molecular regulation of neurotransmitter release. It is thought to play an important role in the synaptic function of specific neuronal systems. SNAP25 associates with proteins involved in vesicle docking and membrane fusion. SNAP25 exists as two alternatively spliced isoforms, SNAP25A and SNAP25B. These isoforms are differentially expressed in neurons and neuroendocrine cells. These two isoforms differ by 9 amino acids in the central portion of the protein.
• Antibody come from
  Synthetic peptide derived from the sphingosine 1-phosphate lyase 1 protein.
• Other description
  Provided as ligand affinity purified antibody in phosphate buffered saline with 0.08% sodium azide. Protein A/G Chromatography
• Clone
  B-29-F9
• Antigen antibody binding interaction
  Mouse anti SNAP25 Antibody
• Antibody is raised in
  Mouse
• Antibody s reacts with
  Human, Mouse, Rat, Monkey, Chicken, Cow
• Antibody s reacts with these species
  This antibody doesn't cross react with other species
• Antibody s specificity
  No Data Available
• Application
  Western Blot, Immunohistochemistry (Paraffin)
• Antibody s suited for
  Antibody can be used for Western blotting (1:400 dilution). Other applications not yet tested. Optimal concentration should be evaluated by serial dilutions.
• Storage
  -20ºC
• Relevant references
  1. Van Veldhoven P.P., et al; Human sphingosine-1-phosphate lyase: cDNA cloning, functional expression studies and mapping to chromosome 10q22. Biochim. Biophys. Acta 1487:128-134(2000)._x000B__x000B_2. Reiss U., et al; Sphingosine-phosphate lyase enhances stress-induced ceramide generation and apoptosis. J. Biol. Chem. 279:1281-1290(2004)._x000B__x000B_3. Nagase T., et al; Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.; DNA Res. 6:337-345(1999)._x000B__x000B_4. Strausberg R.L., et al; Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. 99:16899-16903(2002)._x000B_
• Protein number
  see ncbi
• Warnings
  This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
• Antibody s link
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus

• Gene target
  SNAP25  
• Gene symbol
  SNAP25-AS1, SNAP25
• Short name
  Mouse anti SNAP25
• Technique
  Mouse, anti, antibody to, mouses
• Host
  mouse
• Isotype
  IgG1
• Label
  unlabeled
• Species
  Mouse, Mouses
• Alternative name
  Mouse antibody to synaptosomal-associated protein, 25kDa
• Alternative technique
  murine, antibodies
• Alternative to gene target
  synaptosomal-associated protein, 25kDa, bA416N4.2 and dJ1068F16.2 and RIC-4 and RIC4 and SEC9 and SNAP and SNAP-25, SNAP25 and IDBG-53941 and ENSG00000132639 and 6616, protein binding, Cell surfaces, Snap25 and IDBG-207842 and ENSMUSG00000027273 and 20614, SNAP25 and IDBG-636453 and ENSBTAG00000008323 and 540853

Gene info

• Identity
  HGNC:44312
• Gene
  SNAP25-AS1
• Long gene name
  SNAP25 antisense RNA 1
• Synonyms gene name
  • SNAP25 antisense RNA 1 (non-protein coding)
• GenBank acession
  • AK124961
  • BF244758
  • DA318406
• Locus
  20p12.2
• Discovery year
  2012-08-09
• Entrez gene record
  100131208
• RefSeq identity
  • NR_040710
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000031867

Gene info

• Identity
  HGNC:11132
• Gene
  SNAP25
• Long gene name
  synaptosome associated protein 25
• Synonyms gene
  • SNAP
• Synonyms gene name
  • synaptosomal-associated protein, 25kDa
• Synonyms
  • SNAP-25
  • RIC-4
  • RIC4
  • SEC9
  • bA416N4.2
  • dJ1068F16.2
• Synonyms name
  • resistance to inhibitors of cholinesterase 4 homolog
• Locus
  20p12.2
• Discovery year
  1995-01-24
• Entrez gene record
  6616
• Pubmed identfication
  • 8661740
  • 10692432
• RefSeq identity
  • NM_130811
• Classification
  • SNAREs
• VEGA ID
  OTTHUMG00000031863

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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