RAF-1, phosphorylated (Ser642) (Raf-1, Raf, cRaf, c-Raf, Murine Sarcoma 3611 Oncogene 1, Raf Proto-oncogene Serine/threonine Protein Kinase, v-Raf-1 Murine Leukemia Viral Oncogene Homolog 1)

• Catalog number
  MBS630684
• Price
  Please ask
• Size
  0.1 mL

• Products_type
  Antibody
• Products_short_name
  [RAF-1]
• Products_name_syn
  [Anti -RAF-1, phosphorylated (Ser642) (Raf-1, Raf, cRaf, c-Raf, Murine Sarcoma 3611 Oncogene 1, Raf Proto-oncogene Serine/threonine Protein Kinase, v-Raf-1 Murine Leukemia Viral Oncogene Homolog 1)]
• Other_names
  [RAF1; RAF proto-oncogene serine/threonine-protein kinase; RAF proto-oncogene serine/threonine-protein kinase; Oncogene RAF1; OTTHUMP00000160218; OTTHUMP00000207813; OTTHUMP00000209389; proto-oncogene c-RAF; raf proto-oncogene serine/threonine protein kinase; v-raf-1 murine leukemia viral oncogene homolog 1; Proto-oncogene c-RAF; cRaf; Raf-1]
• Other_gene_names
  [RAF1; RAF1; NS5; CRAF; Raf-1; c-Raf; RAF]
• Clonality
  Polyclonal
• Reactivity
  Rat
• Specificity
  Recognizes rat Raf-1 phosphorylated at serine 642. Species sequence homology: Human, Bovine, Chicken, Mouse, Dog, Primate.
• Purity
  Affinity Purified Purified by immunoaffinity chromatography.
• Form
  Supplied as a liquid in 10mM Hepes, pH 7.5, 150mM sodium chloride, 0.01% BSA, 0.09% sodium azide, 50% glycerol.
• Storage_stability
  May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested_application
  Western Blot (WB)
• Description
  Serine protease, D- or L-serine arginine rich enzyme of serine threonine kinase with serine that is encoded by the codons UCU, UCC, UCA, UCG, AGU and AGC is an ɑ-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH+ 3 form under biological conditions), a carboxyl group. It is non-essential in humans, meaning the body can synthesize it.

• Gene target
  RAF-1   phosphorylated   Ser642   Raf-1   Raf   cRaf   c-Raf   Murine   Sarcoma   3611   Oncogene   Raf   Proto-oncogene   Serine/threonine   Protein   Kinase   v-Raf-1   Murine   Leukemia   Viral   Oncogene   Homolog  
• Gene symbol
  RAF1, RNASE3, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR1289-1, MIR101-1, MIR16-1
• Short name
  RAF-1, phosphorylated (Ser642) (Raf-1, Raf, cRaf, c-Raf, Murine Sarcoma 3611 Oncogene 1, Raf Proto-oncogene Serine/threonine Protein Kinase, v-Raf-1 Murine Leukemia Oncogene Homolog 1)
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  RAF-1, phosphorylated (Ser642) (Raf-1, Raf, cRaf, c-Raf, Murine Sarcoma 3611 Oncogene 1, Raf Proto-oncogene Serine/threonine Protein phosphorylation catalyst, v-Raf-1 Murine Leukemia Viral Oncogene Homolog 1)
• Virus
  leukemia, sarcoma

Gene info

• Identity
  HGNC:9829
• Gene
  RAF1
• Long gene name
  Raf-1 proto-oncogene, serine/threonine kinase
• Synonyms gene name
  • v-raf-1 murine leukemia viral oncogene homolog 1
• Synonyms
  • Raf-1
  • c-Raf
  • CRAF
• Synonyms name
  • C-Raf proto-oncogene, serine/threonine kinase
• GenBank acession
  • X03484
• Locus
  3p25.2
• Discovery year
  1986-01-01
• Entrez gene record
  5894
• Pubmed identfication
  • 1611909
• RefSeq identity
  • NM_002880
• Classification
  • Mitogen-activated protein kinase kinase kinases
  • RAF family
• VEGA ID
  OTTHUMG00000129789
• Locus Specific Databases
  • LRG_413

Gene info

• Identity
  HGNC:10046
• Gene
  RNASE3
• Long gene name
  ribonuclease A family member 3
• Synonyms gene
  • RNS3
• Synonyms gene name
  • ribonuclease, RNase A family, 3
• Synonyms
  • ECP
  • RAF1
• Synonyms name
  • eosinophil cationic protein
• GenBank acession
  • X55990
• Locus
  14q11.2
• Discovery year
  1990-02-24
• Entrez gene record
  6037
• Pubmed identfication
  • 1577491
• RefSeq identity
  • NM_002935
• Classification
  • Ribonuclease A family
• VEGA ID
  OTTHUMG00000029604

Gene info

• Identity
  HGNC:5670
• Gene
  IGHVII-1-1
• Long gene name
  immunoglobulin heavy variable (II)-1-1 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable (II)-1-1
  • immunoglobulin heavy variable (II)-1-1 pseudogene
• Synonyms
  • IGHV(II)-1-1
• GenBank acession
  • AB019441
• Locus
  14q32.33
• Discovery year
  2000-04-17
• Entrez gene record
  28377
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152325

Gene info

• Identity
  HGNC:31499
• Gene
  MIR1-1
• Long gene name
  microRNA 1-1
• Synonyms gene
  • MIRN1-1
• Synonyms
  • hsa-mir-1-1
• Locus
  20q13.33
• Discovery year
  2004-04-23
• Entrez gene record
  406904
• RefSeq identity
  • NR_029780
• Classification
  • MicroRNA MIR1/206 family

Gene info

• Identity
  HGNC:50820
• Gene
  TRUND-NNN8-1
• Long gene name
  tRNA-undetermined (NNN) 8-1
• Synonyms gene name
  • transfer RNA-undetermined (NNN) 8-1
• GenBank acession
  • HG984097
• Locus
  1
• Discovery year
  2014-06-20
• Entrez gene record
  103482528
• Pubmed identfication
  • 18984615

Gene info

• Identity
  HGNC:50819
• Gene
  TRUND-NNN7-1
• Long gene name
  tRNA-undetermined (NNN) 7-1
• Synonyms gene name
  • transfer RNA-undetermined (NNN) 7-1
• GenBank acession
  • HG984096
• Locus
  1
• Discovery year
  2014-06-20
• Entrez gene record
  103482531
• Pubmed identfication
  • 18984615

Gene info

• Identity
  HGNC:5760
• Gene
  IGKV1OR2-1
• Long gene name
  immunoglobulin kappa variable 1/OR2-1 (pseudogene)
• Synonyms gene
  • IGKVPZ1
  • IGKV1OR-1
• Synonyms gene name
  • immunoglobulin kappa variable 1/OR-1
  • immunoglobulin kappa variable 1/OR-1 pseudogene
  • immunoglobulin kappa variable 1/OR-1 (pseudogene)
• Synonyms
  • IGKV1/OR-1
  • IGKV1/OR2-1
• GenBank acession
  • Z12367
• Locus
  2p11.1
• Discovery year
  2000-04-18
• Entrez gene record
  3531
• Pubmed identfication
  • 2853098
• Classification
  • Immunoglobulin kappa (IGK) orphons
• VEGA ID
  OTTHUMG00000155081

Gene info

• Identity
  HGNC:35281
• Gene
  MIR1289-1
• Long gene name
  microRNA 1289-1
• Synonyms gene
  • MIRN1289-1
• Synonyms
  • hsa-mir-1289-1
• Locus
  20q11.22
• Discovery year
  2008-11-03
• Entrez gene record
  100302125
• RefSeq identity
  • NR_031620
• Classification
  • MicroRNA MIR1289 family

Gene info

• Identity
  HGNC:31488
• Gene
  MIR101-1
• Long gene name
  microRNA 101-1
• Synonyms gene
  • MIRN101-1
• Synonyms
  • hsa-mir-101-1
• Locus
  1p31.3
• Discovery year
  2004-04-23
• Entrez gene record
  406893
• RefSeq identity
  • NR_029516
• Classification
  • MicroRNA MIR101 family

Gene info

• Identity
  HGNC:31545
• Gene
  MIR16-1
• Long gene name
  microRNA 16-1
• Synonyms gene
  • MIRN16-1
• Synonyms
  • hsa-mir-16-1
• Locus
  13q14.2
• Discovery year
  2004-04-23
• Entrez gene record
  406950
• RefSeq identity
  • NR_029486
• Classification
  • MicroRNA MIR15/16 family

MeSH Data

• Name
  Leukemia, Experimental
• Concept
  Scope note: Leukemia induced experimentally in animals by exposure to leukemogenic agents, such as VIRUSES; RADIATION; or by TRANSPLANTATION of leukemic tissues.
• Tree numbers
  • C04.557.337.372
  • C04.619.531
  • E05.598.500.496.500
• Qualifiers
  diagnosis, parasitology, immunology, microbiology, diagnostic imaging, physiopathology, rehabilitation, enzymology, etiology, mortality, epidemiology, blood, cerebrospinal fluid, chemically induced, congenital, diet therapy, drug therapy, therapy, psychology, urine, virology, history, classification, economics, embryology, genetics, nursing, radiotherapy, ethnology, prevention & control, pathology, metabolism, complications, surgery

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