anti-Aurora Kinase B Antibody
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Catalog number48-676
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PricePlease ask
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Size0.05 mg
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Gene infoAurora Kinase B (also known as Aurora- and Ipl1-like midbody-associated protein 1, AIM-1, Aurora/IPL1-related kinase 2, Aurora-related kinase 2, STK-1, and Aurora-B) is a Ser/Thr protein kinase member of the Aurora subfamily that may be directly involved in regulating the cleavage of polar spindle microtubules and is a key regulator for the onset of cytokinesis during mitosis. Aurora Kinase B is localized to the midzone of central spindle in late anaphase and concentrated into the midbody in telophase and cytokinesis and is colocalized with gamma tubulin in the mid-body. High levels of Aurora B expression are seen in the thymus, although it is also expressed in the spleen, lung, testis, colon, placenta and fetal liver. Aurora B is expressed during S and G2/M phase and expression is up-regulated in cancer cells during M phase.
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Gene namesAURKB, AIRK2, AIK2, Aurora kinase B, Aurora kinase B-Sv1, Aurora-related kinase 2, Aurora/IPL1-related kinase 2, ARK-2, ARK2, Aurkb-sv1, Aurkb-sv2, Aurora 1, Aurora-B, AIM-1, IPL1, STK-1, STK5, PPP1R48, AurB, Aurora B, Aurora kinase B-Sv2, Aurora-1, Aurora1, Serine/threonine kinase 12, STK1, STK12
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Antibodie s labelunlabelled serum
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PurityImmunoaffinity Chromatography
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Ab raised inRabbit
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TypePolyclonal
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AntigenAurora Kinase B antibody was made against amino acids 227 - 238 of Aurora Kinase B (Human).
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Immuno applicationELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
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Antibody adviceAurora Kinase B antibody can be used in ELISA, Western Blot, immunohistochemistry starting at 5 ug/mL, and immunoprecipitation
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Suspention pH azide0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.
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Keep atStore Aurora Kinase B antibody at 4 grades C or -20 grades C. As with all antibodies avoid freeze/thaw cycles.
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Works withHuman
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Omim nr317373473
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Ncbi nrQ96GD4
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Vial with antibodyin solution
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NCBI GENE nr9212
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GENE symbolAURKB
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Antigene nameaurora kinase B
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SourceHomo sapiens
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Protein nrQ96GD4
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolAURKB, AURKBP1
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Short nameanti-Aurora Kinase B Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toAurora phosphorylation catalyst B (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameaurora kinase B
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Synonyms gene
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Synonyms gene name
- serine/threonine kinase 12
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-01-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Chromosomal passenger complex
- Protein phosphatase 1 regulatory subunits
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameaurora kinase B pseudogene 1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2003-07-21
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Entrez gene record
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data