RK 682, Tyrosine phopshatase inhibitor
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Catalog number
SIH-522-200UG
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Price
Please ask
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Size
200 µg
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Stock availabilitIn Stock
In Stock
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CAS number
150627-37-5
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Description
Tyrosine phopshatase inhibitor
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Molecular weight
368,5 g/mol
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Primary research fields
Cell Signaling
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Other name
RK-682, (R)-3-Hexadecanoyl-5-hydroxymethyltetronic acid, (R)-4-Hydroxy-5-(hydroxymethyl)-3-(1-oxohexadecyl)-2(5H)-furanone
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Product category
Small Molecules
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Product type
Inhibitor
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Chemical formula
C21H36O5
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Origin
Synthetic
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Purity pourcentage
≥98% (HPLC)
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Soluble in
Soluble DMSO, heptane and xylene: ≥8 mg/ml
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Physical appearance
Solid
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Storage recommendations
-20ºC
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Shipping recommendations
Shipped Ambient
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Safety information
Classification: Not a hazardous substance or mixture. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
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PubChem number
54685915
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Scientific context
RK 682 is a specific inhibitor of protein tyrosine phosphatase. It is naturally occurring calcium salt of 3-hexadecanoyl-5-hydroxymethyl-tetronic acid. RK 682 has been shown to inhibit cell cycle progression at G1 phase.
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Bibliography
1. Hamaguchi T., Sudo T., & Osada H. (1995) FEBS Letters. 372(1): 54–58.
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Release date
1-Oct-2014
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PubMed number
Refer to PubMed
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Tested applications
To be tested
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Tested reactivity
To be tested
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Representative figure legend
Chemical structure of RK 682 (SIH-522), a Tyrosine phopshatase inhibitor. CAS #: 150627-37-5. Molecular Formula: C21H36O5. Molecular Weight: 368.5 g/mol. Chemical structure of RK 682, a Tyrosine phopshatase inhibitor (SIH-522). CAS # 150627-37-5. Molecular Formula: C21H36O5.
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Warning information
Non-hazardous
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Country of production
Canada
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Total weight kg
0.25
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Net weight g
0.0002
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Additional description
Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
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Gene target
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Short name
RK 682, Tyrosine phopshatase inhibitor
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Alternative name
RK 682, Tyrosine phopshatase suppressor
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