RK 682, Tyrosine phopshatase inhibitor

  • Catalog number
    SIH-522-200UG
  • Price
    Please ask
  • Size
    200 µg
  • Stock availabilitIn Stock
    In Stock
  • CAS number
    150627-37-5
  • Description
    Tyrosine phopshatase inhibitor
  • Molecular weight
    368,5 g/mol
  • Primary research fields
    Cell Signaling
  • Other name
    RK-682, (R)-3-Hexadecanoyl-5-hydroxymethyltetronic acid, (R)-4-Hydroxy-5-(hydroxymethyl)-3-(1-oxohexadecyl)-2(5H)-furanone
  • Product category
    Small Molecules
  • Product type
    Inhibitor
  • Chemical formula
    C21H36O5
  • Origin
    Synthetic
  • Purity pourcentage
    ≥98% (HPLC)
  • Soluble in
    Soluble DMSO, heptane and xylene: ≥8 mg/ml
  • Physical appearance
    Solid
  • Storage recommendations
    -20ºC
  • Shipping recommendations
    Shipped Ambient
  • Safety information
    Classification: Not a hazardous substance or mixture. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
  • PubChem number
    54685915
  • Scientific context
    RK 682 is a specific inhibitor of protein tyrosine phosphatase. It is naturally occurring calcium salt of 3-hexadecanoyl-5-hydroxymethyl-tetronic acid. RK 682 has been shown to inhibit cell cycle progression at G1 phase.
  • Bibliography
    1. Hamaguchi T., Sudo T., & Osada H. (1995) FEBS Letters. 372(1): 54–58.
  • Release date
    1-Oct-2014
  • PubMed number
    Refer to PubMed
  • Tested applications
    To be tested
  • Tested reactivity
    To be tested
  • Representative figure legend
    Chemical structure of RK 682 (SIH-522), a Tyrosine phopshatase inhibitor. CAS #: 150627-37-5. Molecular Formula: C21H36O5. Molecular Weight: 368.5 g/mol. Chemical structure of RK 682, a Tyrosine phopshatase inhibitor (SIH-522). CAS # 150627-37-5. Molecular Formula: C21H36O5.
  • Warning information
    Non-hazardous
  • Country of production
    Canada
  • Total weight kg
    0.25
  • Net weight g
    0.0002
  • Additional description
    Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
  • Gene target
  • Short name
    RK 682, Tyrosine phopshatase inhibitor
  • Alternative name
    RK 682, Tyrosine phopshatase suppressor
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